Liver scalloping in pseudomyxoma peritonei

Fonseca, Eduardo Kaiser Ururahy Nunes; Martins, Aparecido Nakano; Tridente, Cassia Franco; Yamauchi, Fernando Ide; Baroni, Ronaldo Hueb

doi:10.1007/s00261-017-1092-9

Cited by 6 publications

(4 citation statements)

References 3 publications

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“…9 Liver scalloping, a radiologic sign made by the mass effect of the mucinous neoplasm against the liver and other viscera, is pathognomonic for PMP. 1,2,[4][5][6][7]10 In a retrospective study of 159 patients with PMP, Hotta et al 6 found that visceral scalloping on CT scans correlated with cancer recurrence after CRS. Identifying patients at risk of recurrence is crucial for selecting the appropriate treatment strategy.…”

Section: Discussionmentioning

confidence: 99%

The Cancer Diaspora: A Rare Case of Pseudomyxoma Peritonei of Appendiceal Origin

Bathobakae,

Ozgur,

Jariwala

et al. 2023

Journal of Investigative Medicine High Impact Case Reports

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Pseudomyxoma peritonei (PMP) is a rare clinical entity characterized by widespread mucinous implants in the peritoneal cavity. Commonly seen in females in their 50s, PMP typically originates from ruptured appendiceal mucoceles that find refuge in the peritoneal space. Rarely, PMP may originate from the ovary, stomach, colon, or pancreas. Pseudomyxoma peritonei of colorectal origin is more malignant and has a lower survival rate. We report a case of a 59-year-old Hispanic woman with PMP who presented to the emergency room with a 3-month history of progressive abdominal distention. Pseudomyxoma peritonei was confirmed by computed tomography (CT) scan of the abdomen and pelvis and histopathology, and the patient underwent partial cytoreductive surgery. Given her Eastern Cooperative Oncology Group (ECOG) performance status of 1 despite extensive carcinomatosis, our patient may benefit from hyperthermic intraperitoneal chemotherapy (HIPEC) in the future.

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Section: Discussionmentioning

confidence: 99%

The Cancer Diaspora: A Rare Case of Pseudomyxoma Peritonei of Appendiceal Origin

Bathobakae,

Ozgur,

Jariwala

et al. 2023

Journal of Investigative Medicine High Impact Case Reports

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“…The secretory function of the columnar cells was severely damaged, which led to a decrease in mucus secretion ( 2 , 6 , 18 ). Moreover, the concentrated tumor mass resulted in liver scalloping and omental cake ( 19 , 20 ). The current study results also demonstrated that the presence of omental cake predicted a higher pathological grade.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound for Preoperatively Predicting Pathology Grade, Complete Cytoreduction Possibility, and Survival Outcomes of Pseudomyxoma Peritonei

et al. 2021

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ObjectivesThis study aimed to investigate the value of using ultrasound (US) preoperatively for predicting pathological classification, complete cytoreduction possibility, and survival rate of patients with pseudomyxoma peritonei (PMP).MethodsWe retrospectively studied PMP patients who were scheduled for cytoreductive surgery between May 2009 and October 2019. US examination was performed before surgery. Factors related to high-grade pathology and poor completeness of cytoreduction (CC) score were identified. Associations between ultrasound characteristics and the survival status were also examined to identify independent predictive factors.ResultsPMP patients with clear ascites, abdominal lymph nodes, omental cake, abdominal mass, portal infiltration, and mesenteric involvement visible on US were considered to have high-grade pathology. Various US features were shown to be independent prognostic markers for inadequate cytoreduction in PMP patients. Portal infiltration and mesenteric involvement were significant prognostic factors for lower survival rates (hazard ratio = 3.092, 3.932, respectively). A visual nomogram including these factors was constructed to predict survival rates. The consistency index was 0.777, which reflected relatively high accuracy.ConclusionsPreoperative US has the potential to predict pathological grade and resectability of PMP. Portal infiltration and mesenteric involvement were independent predictors of poor clinical outcomes in PMP patients. Furthermore, a simple-to-use nomogram derived from our study data may be a helpful visual tool in clinical practice to predict 1-, 2-, and 3-year survival rates for PMP patients.

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“… 37 Typically, visceral scalloping, especially liver scalloping suggests mucinous ascites caused by PMP when a subphrenic implant is excluded. 54 Some came up with hypotheses that the imaging of liver scalloping was relevant to the accumulation of mucin deposition and predicted a high risk of recurrence after CRS. 55 When radiologists detect peritoneal nodules, visceral compression and mucinous low density ascites in compartment (Fig.…”

Section: Radiographic Detectionmentioning

confidence: 99%

“…Mucinous neoplasm is perceived when high attenuation peritoneal thickening or masses breaking natural anatomy is shown on computed tomography (CT) images 37. Typically, visceral scalloping, especially liver scalloping suggests mucinous ascites caused by PMP when a subphrenic implant is excluded 54. Some came up with hypotheses that the imaging of liver scalloping was relevant to the accumulation of mucin deposition and predicted a high risk of recurrence after CRS 55.…”

Section: Radiographic Detectionmentioning

confidence: 99%

Comprehensive Understanding and Evolutional Therapeutic Schemes for Pseudomyxoma Peritonei

Zheng

2022

American Journal of Clinical Oncology

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Pseudomyxoma peritonei is an infrequent solid tumor in clinical practice. The low morbidity and deficient understanding of this mucus-secreting malignant disease increase the risks of delayed identification or uncontrollable deterioration. In quite a lot cases, patients go through complete cytoreduction surgery and hyperthermic intraperitoneal chemotherapy could receive a long time survival over 5 years. But the recurrence rate is also hard to overlook. Unlike other types of cancer, the standard treatment for this considerable groups has not been confirmed yet. With the advanced medical progression, studies have been carrying out based on pathogenesis, biological characters, and mutated gene location. All but a few get statistical survival benefits, let alone the breaking progress on research or therapeutic practice in the field. We try to give a comprehensive exposition of pseudomyxoma peritonei around the epidemiology, radiologic features, clinical manifestation, present treatment and promising schemes, hoping to arise much attention and reflection on the feasible solutions, especially for the recrudescent part.

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Liver scalloping in pseudomyxoma peritonei

Cited by 6 publications

References 3 publications

The Cancer Diaspora: A Rare Case of Pseudomyxoma Peritonei of Appendiceal Origin

The Cancer Diaspora: A Rare Case of Pseudomyxoma Peritonei of Appendiceal Origin

Ultrasound for Preoperatively Predicting Pathology Grade, Complete Cytoreduction Possibility, and Survival Outcomes of Pseudomyxoma Peritonei

Comprehensive Understanding and Evolutional Therapeutic Schemes for Pseudomyxoma Peritonei

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