Liver stiffness measurement by 2D SWE from General Electric is similar with Transient Elastography in clinical significant portal hypertension diagnosis

Corina, R.; Procopeţ, Bogdan; Platon, Monica Lupşor; Maniu, Alma; Fischer, Petra; Grigoras, Crina; Bugariu, A.; Tanţău, Marcel; Badea, Radu; Ştefănescu, Horia

doi:10.1016/s0168-8278(18)31531-9

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“…SWE has been successfully used to evaluate breast lesions and cirrhosis. [13][14][15][16][17][18][19][20] In this study, using rabbit model with VX 2 tumors, our aim was to confirm the value of SWE in evaluating the stiffness information during the IRE ablation.…”

Section: Introductionmentioning

confidence: 97%

Irreversible electroporation ablation against subcutaneously implanted VX₂ tumors in rabbits: findings of shearwave ultrasound elastography

Chen

Sheng

et al. 2020

Scott Med J

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Purpose This study aimed to evaluate stiffness changes of rabbit subcutaneous VX2 tumors before and after irreversible electroporation (IRE) ablationby shearwave ultrasound elastography (SWE). Methods IRE was performed on 20 subcutaneously implanted VX2 tumors in rabbits (R-SIVX2). Tumor stiffness was measured by SWE at different time points (before IRE,120minutes after IRE,7 days after IRE and 14 days after IRE). Results Before IRE, the mean stiffness (Emean) of tumors was (10.45 ± 1.07) KPa. 120 minutes after I RE, the Emean of tumors obviously rose to (70.53 ± 9.87) KPa. 7 days after IRE, the Emean of tumors decreased to (40.22 ± 9.01) KPa. 14 days after IRE, the Emean of tumors was (15.17 ± 1.00) KPa. A clear boundary was observed between the ablation area and the normal tissues in the pathological results. Conclusions The stiffness of the VX2 tumors experienced a first rise process and tend to be normal in the procedure of IRE. SWE could provide tissue stiffness information of different IRE ablation period as a non-invasive method.

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Section: Introductionmentioning

confidence: 97%

Irreversible electroporation ablation against subcutaneously implanted VX₂ tumors in rabbits: findings of shearwave ultrasound elastography

Chen

Sheng

et al. 2020

Scott Med J

View full text Add to dashboard Cite

show abstract

Liver stiffness measurement by 2D SWE from General Electric is similar with Transient Elastography in clinical significant portal hypertension diagnosis

Cited by 1 publication

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Irreversible electroporation ablation against subcutaneously implanted VX₂ tumors in rabbits: findings of shearwave ultrasound elastography

Irreversible electroporation ablation against subcutaneously implanted VX₂ tumors in rabbits: findings of shearwave ultrasound elastography

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Liver stiffness measurement by 2D SWE from General Electric is similar with Transient Elastography in clinical significant portal hypertension diagnosis

Cited by 1 publication

References 0 publications

Irreversible electroporation ablation against subcutaneously implanted VX2 tumors in rabbits: findings of shearwave ultrasound elastography

Irreversible electroporation ablation against subcutaneously implanted VX2 tumors in rabbits: findings of shearwave ultrasound elastography

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Irreversible electroporation ablation against subcutaneously implanted VX₂ tumors in rabbits: findings of shearwave ultrasound elastography

Irreversible electroporation ablation against subcutaneously implanted VX₂ tumors in rabbits: findings of shearwave ultrasound elastography