Liver Transplantation for Nonalcoholic Fatty Liver Disease: Role of Bariatric Surgery for Comorbid Obesity

Abstract

Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent form of chronic liver disease throughout the world and is associated with substantial morbidity and mortality related to liver disease and the consequences of metabolic syndrome. NAFLD is projected to become the leading indication for liver transplantation in the United States in the near future, and presents unique challenges due to common comorbidities, particularly obesity. As obesity is often a barrier to transplant, distinctive decision-making and care is needed for this growing population. Bariatric surgery offers a promising option for liver transplant specialists to consider in obese patients with NAFLD cirrhosis. This research highlight reviews the rising burden of NAFLD, concerns regarding obesity and liver transplant, and the potential role of bariatric surgery in the liver transplantation paradigm.Keywords: NAFLD; Cirrhosis; Obesity; Liver Transplantation; Bariatric Surgery To cite this article: Yuval A. Patel, et al. Liver transplantation for nonalcoholic fatty liver disease: role of bariatric surgery for comorbid obesity.