Liver Transplantation in Adults With Wilson’s Disease for the Neuropsychiatric Phenotype: Are We There Yet?

Emerging neurological symptoms after liver transplantation: A 6‐year follow‐up of an adolescent patient with Wilson’s disease

“… 2 It is generally believed that LT can benefit patients with hepatic WD and also improve patients with severe neurological symptoms or mixed type WD, but the survival rate of the latter is lower than that of patients with simple hepatic WD. 3 , 4 And the efficacy and prognosis of LT in patients with neurological WD are always open to debate, 5 , 6 , 7 and we found that a patient with hepatic WD developed neurological symptoms less than a year after successfully receiving LT for acute liver failure at a young age, and that the patient's neurological symptoms continued to worsen over the next 6 years of regular follow‐up and treatment. The findings suggest that we need to further explore the possible mechanisms underlying the neurological symptoms seen in WD after LT and propose improvements to the subsequent treatment regimen.…”