Liver transplantation in malignant primary hepatic neoplasms

González, Enrique Moreno; Gámez, Ramon; García, Ignacio; González-Pinto, I; Loinaz, Carmelo; Ibáñez, Javier; Bercedo, J.; Palomo, Juan Carlos; Palma, F; Vorwald, Peter; Riaño, D; Cerdá, F. Pérez; Dávila, P; Cisneros, C; Maffettone, V.; Sciadini, Marcus F.

doi:10.1016/0002-9610(92)90040-x

Cited by 38 publications

(11 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The largest experience with liver cancers comes from adult transplantation programs [24][25][26][27][28][29][30][31][32]. In the early years of liver transplantation, over 50% of OLT performed by the Cambridge/King's College group was for malignant liver tumors [28].…”

Section: Results With Olt For Liver Tumorsmentioning

confidence: 99%

See 1 more Smart Citation

Liver transplantation for malignant liver tumors in children

Dower

Smith

2000

Med. Pediatr. Oncol.

View full text Add to dashboard Cite

Section: Results With Olt For Liver Tumorsmentioning

confidence: 99%

“…Discouraging results with recurrence of the malignancy and less than 10% long-term survival led to the development of more stringent criteria for transplantation. As a consequence, there has been a reduction to approximately 12% of OLT now being performed for this indication [7,24,27].…”

Section: Results With Olt For Liver Tumorsmentioning

confidence: 99%

Liver transplantation for malignant liver tumors in children

Dower

Smith

2000

Med. Pediatr. Oncol.

View full text Add to dashboard Cite

“…Orthotopic liver transplantation is considered the treatment of choice in patients with nonresectable hepatocellular carcinoma (1)(2)(3)(4). In patients with a tumor confined to the liver, long-term survival with orthotopic liver transplantation is better than with resection or conventional intravenous chemotherapy (1,3).…”

Section: Discussionmentioning

confidence: 99%

“…In patients with impending hepatic failure and nonresectable hepatocellular carcinomas, orthotopic liver transplantation is considered the treatment of choice (1)(2)(3)(4). These patients can wait several months until a suitable donor organ becomes available.…”

mentioning

confidence: 99%

Hepatic Arterial Complications in Liver Transplant Recipients Treated with Pretransplantation Chemoembolization for Hepatocellular Carcinoma

Richard

Silberzweig²,

Mitty³

et al. 2000

Radiology

View full text Add to dashboard Cite

show abstract

“…The 3-and 5-year survival rates range from 16 to 82% and 19.6 to 36%, respectively. [16][17][18][19] Although both resection and transplantation have approximately the same results in terms of 5-year survival, recurrence is much lower in the transplant group if the HCC is > 5 cm in size with fewer than three nodules (82.6% after resection versus 11.1% after transplantation, P < 0.01). 20 Liver metastases are seen in 30 to 50% of patients with colorectal cancer.…”

Section: Surgerymentioning

confidence: 94%

The Treatment of Primary and Metastatic Hepatic Neoplasms Using Percutaneous Cryotherapy

Smith

Ray²

2006

Semin intervent Radiol

View full text Add to dashboard Cite

Cryotherapy has been used clinically in the treatment of metastatic liver malignancies since the 1980s. Rapid freezing to sub-zero temperatures promotes ice formation in the extracellular space and the exit of intracellular water. Cellular death is the result of dehydration, protein denaturation, and microcirculatory failure. Cryotherapy probes use nitrogen or argon gas as a coolant and the development of the ice ball can be monitored using ultrasound, computed tomography, or magnetic resonance imaging. Traditionally, cryotherapy has been performed during laparoscopy or laparotomy, using intraoperative ultrasound for image guidance. A decrease in cryoprobe size (from $ 24 Fr to $ 15 gauge) in conjunction with experience gained in open cryosurgical treatment has allowed the development of minimally invasive percutaneous approaches. In this review, we describe the use of cryotherapy for treatment of primary or secondary liver neoplasms using a percutaneous approach. KEYWORDS: Liver malignancy, ablation, cryotherapyObjectives: Upon completion of this article, the reader should be able to (1) understand the recent advances in cryotherapy, including the expanding clinical indications, (2) review the techniques currently used for cryotherapy of the liver, and (3) present the results reported in the current literature regarding results and complications of percutaneous cryotherapy. Accreditation: Tufts University School of Medicine (TUSM) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit: TUSM designates this educational activity for a maximum of 1 Category 1 credit toward the AMA Physicians Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.Primary and metastatic liver carcinomas have an exceedingly poor prognosis without treatment. For hepatocellular carcinoma (HCC), surgical resection offers the only possible cure. Unfortunately, secondary to multiple reasons such as poor liver reserve, number of metastases, tumor proximity to major vascular or biliary structures, or extrahepatic metastases, only 10% of patients with newly diagnosed HCCs are candidates for resection. Similarly, only 10 to 15% of patients presenting with colorectal liver metastases are candidates for surgical resection.2 Hepatic metastases are the primary cause of death in patients with colorectal cancer.3 Liver metastases are seen in up to 50% of patients with colorectal

show abstract

Liver transplantation in malignant primary hepatic neoplasms

Cited by 38 publications

References 7 publications

Liver transplantation for malignant liver tumors in children

Liver transplantation for malignant liver tumors in children

Hepatic Arterial Complications in Liver Transplant Recipients Treated with Pretransplantation Chemoembolization for Hepatocellular Carcinoma

The Treatment of Primary and Metastatic Hepatic Neoplasms Using Percutaneous Cryotherapy

Contact Info

Product

Resources

About