Abstract-Infertility is the inability or failure to conceive or impregnate after at least one year of unprotected coitus and most of those who suffer from infertility live in developing countries. Its management is supposed to be an important component of reproductive health services. In Nigeria, when infertility occurs, couples seek various treatments, including assisted reproductive technologies. Assisted Reproductive Technologies (ART) is a novel technology which raises a number of challenges with which society has to cope. This review paper describes the issues, goals, prospects and problems of ART in Nigeria. Crucial issues such as the methods of ART available, the cost of ART, statistics of practice and results of ART are discussed. The role of the Government and some non-governmental organizations is outlined. The paper stresses the role of research in solving these problems and finally suggests preventive strategies which may be adopted in other to reduce the incidences of infertility in Nigeria.Index Terms-ART, infertility.