Abstract:Diarrhea-based Irritable Bowel Syndrome (D-IBS) and diarrhea are both associated with ecological imbalance of the gut microbiota. Low Molecular Weight Peptides (LMWP) from the larvae of Musca domestica have been shown to be effective in the treatment of diarrhea and regulation of gut microbiota. Meanwhile, the single polypeptide S3-3 was successfully isolated and identified from LMWP in our previous studies. It remains unclear exactly whether and how LMWP (S3-3) alleviate D-IBS through regulating gut microbiot… Show more
“…Guo et al studied the derivatives of docosahexaenoic acid as candidates for the treatment of ovarian injury in vivo [ 3 ]. Peng et al proposed an extract from Musca domestica as a tool for regulating gut microbiota [ 4 ]. Vanable et al overviewed the state of the art of chemoenzymatic synthesis in the field of natural compounds [ 5 ].…”
“…Guo et al studied the derivatives of docosahexaenoic acid as candidates for the treatment of ovarian injury in vivo [ 3 ]. Peng et al proposed an extract from Musca domestica as a tool for regulating gut microbiota [ 4 ]. Vanable et al overviewed the state of the art of chemoenzymatic synthesis in the field of natural compounds [ 5 ].…”
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