ln-111 Leukocyte Imaging in Disseminated Mycobacterium Avium-lntracellulare Infection

Current Concepts Review: Diagnostic Imaging of the Diabetic Foot

“…This technique is reliable assuming that both radiotracers accumulate in marrow, whereas only WBC's accumulate in infection. 29 Therefore in the presence of osteomyelitis, the labeled leukocytes will amass at the site of infection and this test will be interpreted as a positive. A sulfur colloid scan of the marrow at the same site will be interpreted as negative because it measures bone marrow activity which will be depressed by the infection.…”

“…Palestro et al 29 studied 73 patients scanned with In-111 labeled leukocytes and Tc-99m-sulfur colloid (SC) bone marrow imaging (Level III evidence). There were 22 cases of confirmed infection.…”

“…2 Diabetic foot conditions cause more hospital admissions than any other aspect of the disease and have been reported to result in a mean inpatient stay of 6 weeks. 19,20,29 With approximately 20% of diabetic patients developing a foot ulcer and 6% requiring an amputation, the ability to make an early diagnosis in diabetic patients is critical.…”