Abstract:Background
To investigate the potential role of Long Non-coding RNAs (lncRNAs) in the progression of osteosarcoma.
Methods
The candidate lncRNAs were screened with RNA-seq and confirmed with quantitative real-time PCR. Using MTS, transwell assay, and flow cytometric analysis, the effects of overexpressed lnc-SELPLG-2:1 on cell functions were determined. Immunohistochemical staining, fluorescence in situ hybridization, and luciferase reporter assay … Show more
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