2024
DOI: 10.1080/15476286.2024.2421672
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LncRNAs in melanoma phenotypic plasticity: emerging targets for promising therapies

Tonin Beatriz Cristina Biz,
Castro-Silva Carolina de Sousa,
Slack Frank John
et al.

Abstract: Long non-coding RNAs (lncRNAs) have received growing attention due to their diverse regulatory roles in cancer, including in melanoma, an aggressive type of skin cancer. The plasticity and phenotypic adaptability of melanoma cells are crucial factors contributing to therapeutic resistance. The identification of molecules playing key roles in melanoma cell plasticity could unravel novel and more effective therapeutic targets. This review presents current concepts of melanoma cell plasticity, illustrating its fl… Show more

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