“…Other unusual manifestations included pulmonary involvement, 58,63,68,79 acute arthritis, 52,54,59 carpal tunnel syndrome, 56 calcified breast nodules containing the nematode, 25,53,55,57,72 skin nodules, 25 splenic lesions, 66,90 vein thrombosis, 69 nephrotic syndrome, 48,67,73,86,88 infertility, 61,85 and peripheral neuropathy. 90 Apart from detection in peripheral blood, microfilariae were detected in ascitic fluid, 51 pleural effusion, 58,79 and bronchoalveolar lavage, 68 ovarian follicular fluid, oocytes, and cervicovaginal cytology specimens, 61,78,85 breast and kidney biopsies, 48,55,57,67,86 knee effusion, 52 cerebrospinal fluid and urine, 86 and from spleen tissue after splenectomy. 66 Of those patients presenting with ocular loiasis, 21 were treated with medical therapy (15 with DEC, two with DEC plus mebendazole, two with albendazole, one with ivermectin, and one with ivermectin plus DEC) associated with surgical extraction of the adult worm from the eye.…”