Lobar occlusion of pulmonary arteriovenous malformations with Amplatzer vascular plug

Efficacy, Safety and Characteristics of the Amplatzer Vascular Plug II and IV Utilization for Various Percutaneous Occlusions in Children under 10 Years

“…Moreover, to the best of our knowledge, we report the largest patient series in which AVP II and IV are used to occlude several anatomical shunt varieties including large malformations [8,12,14,16,18,21,[25][26][27][28]. In our experience, AVP II and IV offer excellent paediatric "off-label" alternatives for closure of surgical conduits, aorto-pulmonary collaterals, arterio-venous fistulae, acquired veno-venous communications, sequestration closure, and other miscellaneous lesions [5,8,11,12,15,19]. We also underline that AVP IV seems to be a safe alternative for large CAF occlusions in low-weight infants, even if CAF closure in adults and children offer variable results [6][7]20,28,29].…”

“…Santa Clara, California, 95054 USA) remain frequently used "off-label" in the paediatric population [6][7][8][9][10][11][12][13]. To the exception of PDA closures [13,14], published data on AVP II and IV use in children and infants remain scarce, particularly in regard to the heterogeneity of procedures and outcomes [15][16][17][18][19][20]. The aim of this study is to describe the efficacy, safety, and characteristics of AVP II and IV "off-label" paediatric utilization for various percutaneous vascular occlusions, including very large tubular PDAs, in children under 10 years.…”