Lobectomy For Lung Carcinoma With Ipsilateral Pulmonary Artery Agenesis

Anstadt, Mark P.; Wozniak, Curtis J.; Kathula, Sateesh K.; Sarodia, Bipin D.

doi:10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3836

Cited by 5 publications

(5 citation statements)

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“…A search of the English literature reveals approximately 420 cases of unilateral absence of pulmonary artery (4), while only six cases of lung cancer associated with UAPA have been reported up to date (6)(7)(8)(9)(10)(11). The current patient represents the 7 th reported case of primary lung cancer in UAPA and the 2 nd case of UAPA with primary carcinoma in the contralateral (normal) lung ( Table 1).…”

Section: Discussionmentioning

confidence: 98%

“…The occurrence of lung cancer in patients with UAPA is even rarer and experience with surgical management is very limited. To the authors' knowledge, only six such cases have been reported in the English medical literature (6)(7)(8)(9)(10)(11). In this paper, we describe our experience with UAPA complicated by contralateral lung cancer and make a literature review on this rare clinical condition, focusing on pathology and management strategies.…”

Section: Introductionmentioning

confidence: 99%

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Unilateral absence of pulmonary artery associated with contralateral lung cancer

Zhang

Gao

et al. 2016

J. Thorac. Dis.

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Unilateral absence of a pulmonary artery (UAPA) is a rare congenital cardiac malformation that is often associated with other cardiovascular deformities. Surgical repair of this rare condition is usually performed only on the abnormal lung. The occurrence of lung cancer in association with UAPA is even rarer and clinical experience is very limited. This report aims to describe a case of unilateral absence of right pulmonary artery that was complicated by primary carcinoma of the contralateral lung. A left lower lobectomy was performed despite the absence of the right pulmonary artery and repeated decreases in the arterial oxygen saturation (SaO) were encountered intraoperatively. The current case provides insights into the operative tolerability and the foreseeable ominous prognosis after excision of the normal lung in patients with UAPA and highlights the importance of the clinical awareness of this potentially lethal congenital anomaly in light of its extreme rarity, which may facilitate better diagnosis and treatment of such patients.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Unilateral absence of pulmonary artery associated with contralateral lung cancer

Zhang

Gao

et al. 2016

J. Thorac. Dis.

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“…To our knowledge, this is also the only case of UAPA associated lung cancer in a lifelong nonsmoker. To date, there have been 6 reported cases of UAPA with secondarily associated non-small-cell lung cancer (NSCLC) [17–22]. In all but one case, the primary lung malignancy was completely resected via pneumonectomy or lobectomy.…”

Section: Literature Review and Discussionmentioning

confidence: 99%

“…The latter was the first report of multifocal lung cancer in the setting of pulmonary artery agenesis. In 2011, Anstadt et al presented the only case of ipsilateral lobectomy for lung cancer in the context of UAPA [22]. In contrast, Ito et al reported the only case of postradiotherapy contralateral pulmonary resection (right middle lobectomy) of the normal lung in the setting of left-sided UAPA, outlining the possibility of surgical intervention on the nonaffected lung [17].…”

Section: Literature Review and Discussionmentioning

confidence: 99%

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Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review

Agzarian

Kadlec

Whitehead

et al. 2019

Case Reports in Oncological Medicine

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Unilateral absence of the pulmonary artery (UAPA) represents a rare condition that is often associated with cardiac congenital abnormalities but can also be relatively asymptomatic and indolent. There is a lack of consensus regarding the management of UAPA. However, in the setting of associated complications and ongoing infection, pulmonary resection is advocated. Although rare, the association between UAPA and bronchogenic carcinoma has been previously reported in seven published cases. In the majority of these, anatomic lung resection (most commonly with pneumonectomy) was curative. We present the first reported case of ipsilateral metastatic non-small-cell lung cancer- (NSCLC-) associated UAPA in a 47-year-old patient with ventilator-dependent hypoxic respiratory failure and bronchorrhea, who had been lost to follow-up for 8 years. Initial investigations did not yield evidence of malignancy, and confirmation of metastatic disease was made intraoperatively at the time of thoracotomy. The findings demonstrated evidence of diffuse metastatic pleural disease with lymphangitic carcinomatosis and superimposed infection. The patient was palliated and passed away shortly thereafter. In the setting of UAPA, clinicians should have a high index of suspicion for the possibility of malignancy, and if proven, they should consider early resection following appropriate staging.

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Unilateral absence of pulmonary artery associated with lung cancer: analysis of operation strategy based on digital preoperative planning and surgical simulation with three-dimensional visualization

Liu

Zhang

2021

Surg Radiol Anat

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Lobectomy For Lung Carcinoma With Ipsilateral Pulmonary Artery Agenesis

Cited by 5 publications

References 0 publications

Unilateral absence of pulmonary artery associated with contralateral lung cancer

Unilateral absence of pulmonary artery associated with contralateral lung cancer

Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review

Unilateral absence of pulmonary artery associated with lung cancer: analysis of operation strategy based on digital preoperative planning and surgical simulation with three-dimensional visualization

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