Lobular Breast Cancer in Men: Case Report and Review of the Literature

Abstract

Background: Lobular breast cancer in men is an extremely infrequent occurrence due to the lack of lobules and acini in the male breast. Such a rare case is described here. Case Report: A 74-year-old patient presented with a sizeable lesion in the right breast, which proved to be a lobular carcinoma. Genetic studies excluded Klinefelter’s syndrome, though revealing an interesting genetic multiformity feature. This case represented a lobular carcinoma in a genotypically male patient under no exogenous or endogenous estrogenic influence. Conclusions: The increasing number of male lobular breast cancer cases should be explored more extensively with particular emphasis placed on causally related genetic and hormonal factors.

A Case Report: Lobular Carcinoma In Situ in a Male Patient with Subsequent Invasive Ductal Carcinoma Identified on Screening Breast MRI

“…As a result, LCIS and infiltrating lobular carcinoma are extremely unusual in male patients 6. Nance et al reported the first case of LCIS in a phenotypic and apparently genotypic male in 1989 in association with a large infiltrating lobular carcinoma 7; and in fact, only a limited number of cases of infiltrating lobular carcinoma of the male breast have been reported 8.…”