Lobular capillary hemangiomas: An epidemiologic report, with emphasis on cutaneous lesions

Is pyogenic granuloma associated with Bartonella infection?

“…One epidemiological study of the hormone theory showed that women were not affected significantly more often than men, thereby ruling hormones out as an etiologic factor. 10 A study by Miller et al 11 failed to demonstrate human papillomavirus as the causative agent of LCH.…”

Epulis Gravidarum Manum: Pyogenic Granuloma of the Hand Occurring in Pregnant Women

“…15 There has been much debate concerning the hormonal influence of epulis gravidarum and, more recently, on the cutaneous variant. 8,9 One study of pyogenic granuloma described the lesions to be negative for estrogen and progesterone receptors. 6 Another study found positive estrogen receptors in all samples, including those from men and nonpregnant females.…”

“…Subcutaneous, intravenous, and gastrointestinal lesions have been reported. 1,2,9 The oral variant of pyogenic granuloma occurs more frequently in females, especially pregnant women and those using oral contraceptives. 1,5,6,9 This variant, termed epulis gravidarum, pregnancy tumor, or granuloma gravidarum, is histologically indistinct from the cutaneous type.…”

“…The lesion is a benign vascular tumor that most often arises on the head, trunk, and upper extremities. 1,2,9 The mucosal variant occurs on the lips, gingiva, oral palate, and nasal membranes. 5,9,10 Although the name implies an infectious etiology, sites of previous trauma aggravated by irritation appear to induce the inflammatory and hyperplastic reaction.…”

“…1,2,9 The mucosal variant occurs on the lips, gingiva, oral palate, and nasal membranes. 5,9,10 Although the name implies an infectious etiology, sites of previous trauma aggravated by irritation appear to induce the inflammatory and hyperplastic reaction. 1,2,4,7 Bacterial or viral infection, as well as tumor angiogenic factors, have also been implicated.…”