Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial

Ezeh, Uche; Shoulder, V.S; Breeson, Anthony; Lamb, Martin; Vellacott, I. D.; Martin, Jeffrey

doi:10.1016/s0140-6736(95)92112-5

Cited by 37 publications

(26 citation statements)

References 15 publications

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“…Our data support these studies and confirmed the limited duration of the local anesthetic effect with decreased narcotic use and pain scores on the day of surgery and the first postoperative day but no differences on the second postoperative day. Most previous studies included only minor gynecologic procedures such as tubal ligations, adhesiolysis, and adnexal procedures [19][20][21][22][23][24][25][26]. The results of our study as well as a study by Cruz et al [16] demonstrated that the superior pain control achieved with intraperitoneal administration of local anesthetic extends to patients undergoing minimally invasive hysterectomies and cancer staging procedures.…”

Section: Discussionsupporting

confidence: 63%

Effect of intraperitoneal bupivacaine on post-operative pain in the gynecologic oncology patient

Rivard¹,

Teoh²

2014

Gynecologic Oncology

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Section: Discussionsupporting

confidence: 63%

Effect of intraperitoneal bupivacaine on post-operative pain in the gynecologic oncology patient

Rivard¹,

Teoh²

2014

Gynecologic Oncology

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“…However, the incidence of reported abdominal pain probably encompasses these two types of pain. In the literature this pain has been reported to last no more than six hours, and can often be prevented or at least decreased by the topical administration of 0.5% bupivacaine, as was done in this study (Ezeh et al, 1995;Goldstein et al, 2000;Wheatley, Millar, & Jadad, 1994). By the time the bupivacaine had worn off, this pelvic pain would have largely subsided.…”

Section: Discussionsupporting

confidence: 49%

“…The review of literature supported the analgesic effectiveness of this technique in the immediate postoperative period and I elected to standardize its use in this study as part the multimodal approach to postoperative pain (Ezeh et al, 1995;Goldstein et al, 2000;Wheatley et al, 1994).…”

Section: Theoretical Framework Used To Guide Researchmentioning

confidence: 97%

The Effect of Pre-Emptive Administration of Dextromethorphan on Postoperative Pain in Patients Undergoing Interval Laparoscopic Tubal Sterilization

Pitcher¹

2001

PsycEXTRA Dataset

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Public reportino burden for tNs collection of information is estimated to average 1 hour per response, including the time for reviewing inslnictions, searching existing data sources, gathering and maintaining the date needed, and completing and reviewing the collection of information. Send comments regarding tNs burden estimate or any other aspect of tNs collection of information, including suggestions for reducing tNs burden, TITLE AND SUBTITLEThe effect of pre-emptive administration of dextromethorphan on postoperative pain in patients undergoing interval laparoscopic tubal sterilization AUTHOR(S)CPT Brian M. Pitcher PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES)University Each year an estimated one million women elect to have surgical sterilization. This is performed by a laparoscopic procedure which can be severe enough to warrant an unplanned admission. With an increased understanding of the physiological basis of pain, classes of drugs not normally associated with pam reduction are now being investigated based on their ability to mteract with receptors in the pain pathway. Experimental studies have shown that the N-methyl-D-aspartate (NMDA) receptor plays a significant role in neuronal "wind-up", a state of hyperalgesia that can last from hours to days following injury or trauma.. Interfering with the NMDA receptor prior to surgical stimuli, wmd-up is prevented resuUing in decreased pain and analgesic requirements followmg surgery. Dextromethorphan, a readily available nonopioid antimssive in clinical use for more than 40 years, is one such NMDA receptor Anticosti. This prospective, randomized, double blind pilot study compared the effects over time when patients received dextromethorphan versus placebo-emptively. The sample was comprised of 14 subjects undergomg laparoscopic tubal ligation under general endotracheal anesthesia at regional military medical center for the Pacific Basin. Patients were ASA physical category I or II and at least 18 years of age and assigned to one of two groups. Group I received 60 mg of dextromethorphan orally, and Group II received an oral placebo. Postoperative pain was assessed using an 11 point Numeric Rating Scale (NRS) at eight time intervals. Additionally, a follow-up questionnaire and 48-hour postoperative telephone call were used to collect data on the patients' satisfaction of being in the study. The Student's t-test was used to determine homogeneity between the two groups. Following analysis, a statistically significant difference was found in two areas. Patients who received dextromethorphan 60 mg orally before surgery had a significant decrease m postoperative pain (p<0.04). The amount of Roxicet required postoperative was statistically less in the dextromethorphan group (p<0.02). The preoperative use of dextromethorphan may significantly decreased the amount of postoperative pain experienced with a resultant decrease in need for narcotic analgesics. This prospective, randomized, double blind pilot study compared the effects over time when patients received de...

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“…Sample size calculation was based on variance obtained from a previous study by Ezeh et al [4], and was based on anticipated group-specific medians. With the primary objective of finding a difference in analgesia in the 3 groups, a minimum of 24 women were required in each group to obtain a power of 90%, with type 1 error of 0.05.…”

Section: Methodsmentioning

confidence: 99%

“…Pressure or ischemia caused by a Silastic ring at the ligation site contributes to the pain [2,3]. This justifies application or injection of local anesthetic agents at the site of Falope ring application [4,5]. Nonsteroidal anti-inflammatory drugs have also been evaluated with regard to analgesic potency in managing postoperative pain after laparoscopy, with conflicting results.…”

mentioning

confidence: 99%

Comparison of Lignocaine Gel–Soaked Falope Rings vs Rectal Diclofenac Suppository for Pain Relief in Laparoscopic Sterilization

Sharma

Ghosh

Kumar

et al. 2011

Journal of Minimally Invasive Gynecology

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Local anaesthetic on Filshie clips for pain relief after tubal sterilisation: a randomised double-blind controlled trial

Cited by 37 publications

References 15 publications

Effect of intraperitoneal bupivacaine on post-operative pain in the gynecologic oncology patient

Effect of intraperitoneal bupivacaine on post-operative pain in the gynecologic oncology patient

The Effect of Pre-Emptive Administration of Dextromethorphan on Postoperative Pain in Patients Undergoing Interval Laparoscopic Tubal Sterilization

Comparison of Lignocaine Gel–Soaked Falope Rings vs Rectal Diclofenac Suppository for Pain Relief in Laparoscopic Sterilization

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