Local anesthetic toxicity and lipid resuscitation in pregnancy

Bern, Sarah; Weinberg, Guy

doi:10.1097/aco.0b013e32834654df

Cited by 68 publications

(40 citation statements)

References 34 publications

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“…This is particularly pertinent in the obstetric population as physiological changes of pregnancy may increase the risk of LAST in parturients. 271 Several measures may help mitigate the risk of LAST and should be used whenever possible. Epinephrine will reduce peak local anesthetic plasma concentration 121,136 and should always be added to the injectate solution.…”

Section: Local Anesthetic Systemic Toxicitymentioning

confidence: 99%

Essentials of Our Current Understanding

Chin

McDonnell

Carvalho

et al. 2017

Regional Anesthesia and Pain Medicine

364

208

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Abdominal wall blocks rely on the spread of local anesthetic within musculofascial planes to anesthetize multiple small nerves or plexuses, rather than targeting specific nerve structures. Ultrasonography is primarily responsible for the widespread adoption of techniques including transversus abdominis plane and rectus sheath blocks, as well as the introduction of novel techniques such as quadratus lumborum and transversalis fascia blocks. These blocks are technically straightforward and relatively safe and reduce pain and opioid requirements in many clinical settings. The data supporting these outcomes, however, can be inconsistent because of heterogeneity of study design. The extent of sensory blockade is also somewhat variable, because it depends on the achieved spread of local anesthetic and the anatomical course of the nerves being targeted. The blocks mainly provide somatic analgesia and are best used as part of a multimodal analgesic regimen. This review summarizes the anatomical, sonographic, and technical aspects of the abdominal wall blocks in current use, examining the current evidence for the efficacy and safety of each.

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Section: Local Anesthetic Systemic Toxicitymentioning

confidence: 99%

Essentials of Our Current Understanding

Chin

McDonnell

Carvalho

et al. 2017

Regional Anesthesia and Pain Medicine

364

208

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“…Still, much remains to be investigate about the use of lipid emulsions, but judging by the lack of adverse effects to date 21 , expectations are encouraging and even recommended for accidents in case of obstetric anesthesia 22 .…”

Section: Discussionmentioning

confidence: 99%

Terapia lipídica com dois agentes na intoxicação por ropivacaína: estudo experimental em suínos

Bonfim¹,

Melo²,

Dreyer³

et al. 2012

Rev. Bras. Anestesiol.

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“…The report also highlights the potential value of a modified early obstetric warning score. In a more recent publication, using a large British ICU data set, Carle et al 28 described the evaluation of several preexisting obstetric early warning scores and the development and validation of a new obstetric score and demonstrated excellent discrimination between survivors and nonsurvivors for this new score (area under the receiver-operating characteristic curve, 0.995). These scores can be used to monitor patients by clinical use of an early warning score chart ( Figure 1) and can accurately identify patients at high risk of mortality, although not specifically mortality resulting from cardiac arrest.…”

Section: Severity Of Illness and Early Warning Scoresmentioning

confidence: 99%

Cardiac Arrest in Pregnancy

Jeejeebhoy¹,

Zelop²,

Lipman³

et al. 2015

Circulation

324

111

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Abstract-This is the first scientific statement from the American Heart Association on maternal resuscitation. This document will provide readers with up-to-date and comprehensive information, guidelines, and recommendations for all aspects of maternal resuscitation. Maternal resuscitation is an acute event that involves many subspecialties and allied health providers; this document will be relevant to all healthcare providers who are involved in resuscitation and specifically maternal resuscitation. Key Words: AHA Scientific Statements ■ cardiopulmonary resuscitation ■ heart arrest ■ pregnancy © 2015 American Heart Association, Inc.Circulation is available at http://circ.ahajournals.org DOI: 10.1161/CIR.0000000000000300The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest.This statement was approved by the American Heart Association Science Advisory and Coordinating Committee on July 6, 2015, and the American Heart Association Executive Committee on August 24, 2015. A copy of the document is available at http://my.americanheart.org/statements by selecting either the "By Topic" link or the "By Publication Date" link. To purchase additional reprints, call 843-216-2533 or e-mail kelle.ramsay@wolterskluwer.com.The online-only Data Supplement is available with this article at http://circ.ahajournals.org/lookup/suppl/doi:10.1161/CIR.0000000000000300/-/DC1. The American Heart Association requests that this document be cited as follows: Jeejeebhoy FM, Zelop CM, Lipman S, Carvalho B, Joglar J, Mhyre JM, Katz VL, Lapinsky SE, Einav S, Warnes CA, Page RL, Griffin RE, Jain A, Dainty KN, Arafeh J, Windrim R, Koren G, Callaway CW; on behalf of the American Heart Association Emergency Cardiovascular Care Committee, Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation, Council on Cardiovascular Diseases in the Young, and Council on Clinical Cardiology. Cardiac arrest in pregnancy: a scientific statement from the American Heart Association. Circulation. 2015;132:1747-1773 Expert peer review of AHA Scientific Statements is conducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit http://my.americanheart.org/statements and select the "Policies and Development" link.Permissions: Multiple copies, modification, alteration, enhancement, and/or distribution of this document are not permitted without the express permission of the American Heart Association. Instructions for obtaining permission are located at http://www.heart.org/HEARTORG/General/CopyrightPermission-Guidelines_UCM_300404_Article.jsp. A link to the "Copyright Permissions Request Form" appears on the right ...

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Local anesthetic toxicity and lipid resuscitation in pregnancy

Cited by 68 publications

References 34 publications

Essentials of Our Current Understanding

Essentials of Our Current Understanding

Terapia lipídica com dois agentes na intoxicação por ropivacaína: estudo experimental em suínos

Cardiac Arrest in Pregnancy

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