Local Calcitriol Injections as a Suppressive Treatment of Secondary Hyperparathyroidism in Chronic Dialysis Patients

Abstract

Parathyroid adenoma injection is an alternative method of treatment for some patients resistant to treatment by means of vitamin D3 pulses or intravenous administration of calcitriol. The success of treatment is to a great extent determined by proper selection of patients and the taking of decisions when the period of secondary hyperparathyroidism is not very advanced.

Microwave ablation of hyperplastic parathyroid glands is a treatment option for end-stage renal disease patients ineligible for surgical resection

“…Several case reports and case series have been published. Percutaneous injection of ethanol [21,22], acetic acid [23] and calcitriol [24] and thermal ablation, including radiofrequency (RF) [25,26], laser [27] and high-intensity focussed ultrasound (HIFU) [28,29], have been assessed in patients with hyperparathyroidism. A preliminary study by our group also confirmed that ultrasound-guided MWA was safe and effective in destroying parathyroid gland tissue in patients with SHPT [15,16].…”