Local effects of usage of oropharyngeal antiseptics (Cetylpyridinium chloride) in oral inflammatory conditions and oral surgical interventions.

Abstract

Cetylpyridinium Chloride belongs to a group of cationic quaternary ammonium compounds. Its properties are widely used for local treatment of inflammatory conditions in the oral cavity, as well as for a complementary treatment after oral surgical interventions to ease the postoperative pain and reduce the postoperative inflammation. The examined sample consisted of sixty patients divided into two main groups. The first group consisted of examinees in which an oral surgery with cumulative soft tissue and bone trauma was indicated, while the second group included examinees with symptoms of pericoronitis. During the study, the parameters we examined were: pain, inflammation, index of gingival bleeding, index for determining the depth of the pericoronary pocket and we compared the values obtained at the first, second and third visit. During that period, solutions based on cetylpyridinium were used for rinsing. The results were statistically processed and on that basis, a definite standpoint was taken for the therapeutic efficacy and safety in treated patients. Clinically verified results from this study confirm the properties of cetilpyridine and its ability to reduce pain in the postoperative period and reduce local tissue inflammation. These data encouraged us to propose topical application of antiseptic solutions in the preoperative period for conditioning oral tissues and reducing microbial load and plaque control as well as its prolonged use 7 days after oral surgery.