Local Hemostasis of Nephrostomy Tract with Fibrin Adhesive Sealing in Percutaneous Nephrolithotomy

Initial Experience with Hemostatic Fibrin Glue as Adjuvant during Tubeless Percutaneous Nephrolithotomy

“…[7][8][9] In 1987, Pfab et al, 11,12 after initial animal experiments, administered collagen fibrin adhesive to the nephrostomy tract during the placement of a 5F or 10F nephrostomy catheter. They noted excellent hemostasis in all 26 cases, "decreasing the risk of a protracted venous or arterial hemorrhage from the parenchymal canal and obviating the need for [sic] a larger nephrostomy tube.…”

A Prospective, Randomized Trial Evaluating the Safety and Efficacy of Fibrin Sealant in Tubeless Percutaneous Nephrolithotomy

“…11 Recently a fibrin sealant was successfully used in PCNL for its hemostatic and sealant properties. 4,6,12 In 1987 Pfab 4 They reported a decreased hospital stay without affecting the hematocrit decrease and analgesic use. CT done in 13 patients 1 to 3 weeks after surgery revealed no complications arising from fibrin sealant administration or any evidence of fibrin along the PCNL tract.…”

Haemostasis in Urology: Mechanism and Pharmacology

“…Fibrin glue has its use, again in combination with collagen fleece, wrapped around a small catheter which can be placed down the sheath prior to removal. The small size catheter was also more comfortable for the patient (Pfab et al, 1987). Gazelle et al (1990 reported the use of a thrombincoated protein polymer sheath in enhancing haemostasis at percutaneous biopsy, which is clearly important in full thickness renal biopsies.…”