Local Inflammatory Response Can Predict Clinical Outcome in Patients with Curatively Resected Stage-IIB Colon Cancer: An Advanced Methodological Study

Risk stratification and prognosis prediction based on inflammation‐related gene signature in lung squamous carcinoma

“…Several studies targeted the predictive value of inflammatory factors or immune cells and revealed that high inflammation level was correlated with poor outcomes. 26 , 27 , 28 , 29 , 30 A previous study reviewed 2334 patients with gastric cancer and built a model using inflammatory biomarkers. 26 Mehmet Zengin used several methods to evaluate the local inflammatory response, which is an indicator of colon cancer.…”

“… 26 Mehmet Zengin used several methods to evaluate the local inflammatory response, which is an indicator of colon cancer. 27 Another study mentioned that a neutrophil‐to‐lymphocyte ratio is a useful serum biomarker of non‐small cell lung cancer (NSCLC). 28 These studies mainly focused on peripheral blood cell proportions and acute‐phase protein levels.…”

“…The connection between inflammation and cancer is widely accepted. Several studies targeted the predictive value of inflammatory factors or immune cells and revealed that high inflammation level was correlated with poor outcomes 26–30 . A previous study reviewed 2334 patients with gastric cancer and built a model using inflammatory biomarkers 26 .…”

Tumour budding in preoperative biopsy specimens is a useful prognostic index for identifying high-risk patients in early-stage (pN0) colon cancer

“…Briefly, histopathological evaluations can be divided intrabiopsy evaluation (section, area and focus) and extrabiopsy evaluation (staining, magnification, and counting). Model A [17] was used for intrabiopsy evaluation and method 1 [18] was used for extrabiopsy evaluation. And both of these methods yielded successful results.…”

“…Many different methods have been used in the literature to evaluate BD [8][9][10][11][12][13][14]. This study was based on two successful methods, model A and method 1 [17,18]. Model A recommends using the hot spot area, deepest invasive block, invasive margin.…”