Quantum correlation plays an important role in quantum information processing, for which various quantifiers have been proposed so far. In this paper, we address the dynamics of local quantum uncertainty (LQU) as a reliable quantifier of quantum correlation in a two-qubit Heisenberg spin chain in the presence of nonuniform external magnetic field and Dzyaloshinski-Moriya interaction with intrinsic decoherence. The influences of the initial states, external magnetic field strength, Dzyaloshinski-Moriya interaction strength and intrinsic decoherence rate on the dynamics of LQU have been in detail investigated. Our analytical results show that the dynamics of LQU is strongly depended on the form of initial states. For an initial correlated state, the dynamical behaviors of LQU exhibit either monotonic decay or damped oscillations with respect to time. While for an initial separable state, quantum correlation quantified by LQU can be created due to the Dzyaloshinski-Moriya interaction and Heisenberg anisotropic interaction. Besides, the relationship between LQU and l-norm coherence or concurrence is also demonstrated in the present model.