Local staging of endometrial carcinoma: role of multidetector CT

Tsili, Athina C.; Tsampoulas, C.; Dalkalitsis, N; Stefanou, Dimitrios; Paraskevaidis, E.; Efremidis, Stavros C.

doi:10.1007/s00330-007-0839-z

Cited by 24 publications

(8 citation statements)

References 29 publications

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“…17 Recent studies done to assess preoperatively, the myometrial and cervical extension of endometrial carcinoma with multidetector CT showed better diagnostic accuracy of 95% and 81%, respectively. 18 At present, CT is used generally in the assessment of advanced stage disease, i.e. for evaluating patients with endometrial carcinoma by determining nodal and distant metastases.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy Of Pelvic Mri For Determination Of The Cervical Involvement In Endometrial Cancer

Masroor

Rashid

Afzal

et al. 2018

J Coll Physicians Surg Pak

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Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy Of Pelvic Mri For Determination Of The Cervical Involvement In Endometrial Cancer

Masroor

Rashid

Afzal

et al. 2018

J Coll Physicians Surg Pak

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“…Recently, Tsili et al studied patients who underwent CT before resection of endometrial cancer but their study was limited by a small number of patients ( n = 21) and also relied on the1988 FIGO staging system. 15 …”

Section: Discussionmentioning

confidence: 99%

Diagnostic Performance of Computed Tomography for Preoperative Staging of Patients with Non-endometrioid Carcinomas of the Uterine Corpus

et al. 2015

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Purpose The aim of this study was to assess the diagnostic performance of computed tomography (CT) for initial staging of non-endometrioid carcinomas of the uterine corpus. Materials and Methods Waiving informed consent, the Institutional Review Board approved this Health Insurance Portability and Accountability Act (HIPAA)-compliant retrospective study of 193 women with uterine papillary serous carcinomas, clear cell carcinomas, and carcinosarcomas, who underwent surgical staging between May 1998 and December 2011 and had preoperative CT within 6 weeks before surgery. Two radiologists (R1, R2) independently reviewed all CT images. Sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), and area under the curve were calculated using operative notes and surgical pathology as the reference standard. Results The respective sensitivities and specificities achieved by R1/R2 were 0.79/0.64 and 0.87/0.75 for detecting deep myometrial invasion (MI) on CT; 0.56/0.63 and 0.93/0.79 for detecting cervical stromal invasion; 0.52/0.45 and 0.95/0.93 for detecting pelvic nodal metastases; and 0.45/0.30 and 0.98/0.98 for detecting para-aortic nodal metastases. Although CT had suboptimal sensitivity for the detection of omental disease, it had high PPV for omental seeding at surgical exploration (1.00 for R1 and 0.92 for R2). Inter-observer agreement ranged from moderate in the detection of deep MI (κ = 0.42 ± 0.06) to almost perfect in the detection of para-aortic nodal metastases (κ = 0.88 ± 0.08). Conclusion In patients with uterine non-endometrioid carcinomas, CT is only moderately accurate for initial staging but may provide clinically valuable information by ‘ruling-in’ isolated para-aortic lymph node metastases and omental dissemination.

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“…These studies considered axial CT scans only, so that the detection of local invasion was difficult to assess. A recent study that assessed the accuracy of multidetector CT with MPR in the local staging of endometrial carcinoma found it to have a sensitivity, specificity, and accuracy of 100%, 80%, and 95%, respectively, in evaluating myometrial invasion, and of 78%, 83%, and 81%, respectively, in assessing cervical infiltration (51). Use of off-axial images, particularly in the sagittal orientation, may ting.…”

Section: Malignant Conditionsmentioning

confidence: 95%

Added Value of Multiplanar Reformation in the Multidetector CT Evaluation of the Female Pelvis: A Pictorial Review

Yitta¹,

Hecht²,

Slywotzky³

et al. 2009

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Although computed tomography (CT) is generally not the first-line imaging test of choice for the evaluation of female pelvic disorders, it is often the initial diagnostic examination performed in the emergency setting in patients who present with abdominal pain and nonspecific clinical symptoms. Multidetector CT coupled with reconstruction software permits isotropic voxel acquisition that can be used to generate two-dimensional multiplanar reformatted (MPR) images for evaluation of the female pelvis with no additional radiation exposure. Multidetector CT with MPR allows improved visualization of the normal anatomy and anatomic variants as well as greater diagnostic accuracy in the evaluation of the female pelvis. Although ultrasonography and magnetic resonance imaging remain the primary imaging modalities for the assessment of most female pelvic disorders, more accurate diagnosis of these disorders at multidetector CT may obviate additional imaging tests and allow more appropriate management.

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Local staging of endometrial carcinoma: role of multidetector CT

Cited by 24 publications

References 29 publications

Diagnostic Accuracy Of Pelvic Mri For Determination Of The Cervical Involvement In Endometrial Cancer

Diagnostic Accuracy Of Pelvic Mri For Determination Of The Cervical Involvement In Endometrial Cancer

Diagnostic Performance of Computed Tomography for Preoperative Staging of Patients with Non-endometrioid Carcinomas of the Uterine Corpus

Added Value of Multiplanar Reformation in the Multidetector CT Evaluation of the Female Pelvis: A Pictorial Review

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