Local therapy for prostate-specific antigen recurrence after definitive treatment

Meng, Maxwell V.; Carroll, Peter R.

doi:10.1038/sj.pcan.4500497

Prostate Cancer Prostatic Dis

2001

DOI: 10.1038/sj.pcan.4500497

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Local therapy for prostate-specific antigen recurrence after definitive treatment

Maxwell V. Meng

Peter R. Carroll

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2002

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References 49 publications

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Avoidance and management of positive surgical margins before, during and after radical prostatectomy

Bott¹,

Kirby

2002

Prostate Cancer Prostatic Dis

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Positive surgical margins after radical prostatectomy lead to an increased risk of progression and reduced disease free survival. Earlier detection of prostate cancer, appropriate patient selection and improved operative techniques can reduce the incidence of positive margins, though the risk can not be eliminated as preoperative staging techniques are not sufficiently sensitive. Nerve sparing and bladder neck sparing do not adversely affect margin status in appropriately selected men. Once positive margins have been diagnosed the optimal management and the timing of treatment remains controversial. Adjuvant radiotherapy or salvage radiotherapy in men with a low PSA may improve local control and PSA free survival in some individuals, a survival benefit has not yet been established.

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Avoidance and management of positive surgical margins before, during and after radical prostatectomy

Bott¹,

Kirby

2002

Prostate Cancer Prostatic Dis

View full text Add to dashboard Cite

show abstract

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Local therapy for prostate-specific antigen recurrence after definitive treatment

Cited by 1 publication

References 49 publications

Avoidance and management of positive surgical margins before, during and after radical prostatectomy

Avoidance and management of positive surgical margins before, during and after radical prostatectomy

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