Local Tumor Bed Recurrence Following Partial Nephrectomy in Patients with Small Renal Masses

Abstract

Local tumor bed recurrence after partial nephrectomy is associated with several preoperative factors, including multiple tumors and a solitary kidney, as well as intraoperative and postoperative factors such as a positive surgical margin and higher pathological stage.

Recurrence after radical and partial nephrectomy in high complex renal tumor using propensity score matched analysis

“…RN radical nephrectomy, PN partial nephrectomy, BMI body mass index, DM diabetes mellitus, HTN hypertension, ECOG Eastern cooperative oncology group performance status, MDRD modification of diet in renal disease, GFR estimated glomerular filtration rate, R radius (maximal diameter), E exophytic/endophytic, N nearness to collecting duct system/renal sinus, A anterior/posterior location, L location relative to the polar lines. www.nature.com/scientificreports/ follow-up imaging or (2) the detection of a new enhancing lesion in the same region of the ipsilateral kidney as the original PN site (e.g., the PN site and the recurrence site were both in the lower pole) 6 . Systemic recurrence was defined as tumor development at systemic distant sites or in non-regional retroperitoneal LNs 8 .…”

“…Nevertheless, 20-40% of the patients treated for the localized case were reported to have recurrences 5 . In a multicenter study, Shah et al observed that the disease recurred in 5.6% of the patients treated with PN for clinically localized RCC 6 . With the number of PN increasing in the last few years, growing attempts have been made to implement PN even for high complex renal tumors described by RENAL nephrometry score (RENAL), developed as a useful evaluation tool for predicting operative complexity posed by warm ischemic time (WIT) or postoperative complications 7 .…”

Recurrent papillary renal cell carcinoma with concomitant ipsilateral upper urinary tract urothelial carcinoma and metachronous urothelial carcinoma of the bladder

“…Larger tumors (median 4.1 cm) and higher clinical stage at presentation (cT3 or greater) are associated with local tumor bed recurrence, both of which were present in this patient. 5 It is fitting that a similar risk stratification profile would predict disease recurrence in cases of concomitant UTUC.…”

Local recurrences after laparoscopic resections for renal parenchymal cancer

“…Согласно данным мировой литературы, случаи ре-цидива рака почки после выполнения резекции почки колеблются от 0 до 10,6 % [7][8][9][10]. В нашем исследо-вании местные рецидивы после проведенных ЛРП при сроке наблюдения от 3 до 71 мес (в среднем 8,6 мес) [11].…”