Localisation of osteogenic and osteoclastic cells in porous β-tricalcium phosphate particles used for human maxillary sinus floor elevation

Periodontal regeneration following application of basic fibroblast growth factor-2 in combination with beta tricalcium phosphate in class III furcation defects in dogs

“…The resorption of β-TCP in vivo involves chemical dissolution 33,34) and phagocytosis by osteoclasts 15,17) . β-TCP remained in 22.4±6.3% of the furcation area in the TF group.…”

“…β-TCP, which belongs to the group of bioactive bioceramics of completely synthetic origin, is well known as a biodegradable material with good osteoconductive capacity and clinical efficacy [17][18][19][20] . Recently, we demonstrated that tunnel structured β-TCP induced an increase in cells and blood vessels derived from the residual bone when compared with β-TCP composed of macropores with small connecting area, which enhanced periodontal regeneration in class III furcation defects 21) .…”

Periodontal repair following implantation of beta-tricalcium phosphate with different pore structures in class III furcation defects in dogs

“…Therefore, we hypothesized that vascularization would enable delivery of cells and supply of nutrients and oxygen to the cells during the initial healing stage without the the small connecting area between macropores. Beta-tricalcium phosphate (β-TCP) belongs to the group of bioactive bioceramics of completely synthetic origin and has been used in periodontology as a bone graft substitute since the 1980s 1,[20][21][22][23] . At present, there are various types of β-TCP composed of macropores with small connecting area [24][25][26] .…”

Effects of α-DT cement with hydroxypropyl cellulose on bone augmentation within a titanium cap in the rabbit calvarium

“…On degradation of biomaterials, Lu et al 17) and Zerbo et al 18) reported that for β-TCP particles, their predominant cause of degradation was attributed to chemical dissolution whereas osteoclasts played only a minor role in their replacement by bone. As for α-TCP particles, Yamada et al 19) reported that they were chemically dissolved by tissue fluids and absorbed by osteoclast-like cells.…”