Localisation tubaire et ovarienne d’une malakoplakie: à propos d’un cas et revue de la littérature

Boubess, Ikram; Ouassour, Salma; Tazi, M; Filali, Adib; Alami, Mohammad Hassan

doi:10.11604/pamj.2015.22.17.6561

Pan Afr Med J

2015

DOI: 10.11604/pamj.2015.22.17.6561

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Localisation tubaire et ovarienne d’une malakoplakie: à propos d’un cas et revue de la littérature

Ikram Boubess¹,

Salma Ouassour²,

M Tazi³

et al.

Abstract: La malakoplakie est une pathologie inflammatoire rare qui résulte d'un déficit de la fonction phagocytaire macrophagique. Il n'existe pas de symptomatologie spécifique de la maladie mais dépendante de l'organe touché. Nous rapportons un cas rare de malakoplakie annexielle chez une femme de 36 ans qui a été opérée pour suspicion de cancer ovarien et dont le diagnostic de malakoplakie ne s'est fait qu’à l'examen anatomopathologique. La malakoplakie touche essentiellement le tractus urogénital et le diagnostic po… Show more

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Cited by 3 publications

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Bilateral Ovarian Malakoplakia: Case Report and Review of the Literature With Clinical and Diagnostic Considerations

Carbone

Bonometti

Cassani

et al. 2019

International Journal of Gynecological Pathology

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Malakoplakia is a rare condition in which histiocytic cells accumulate within different organs and tissues, sometimes mimicking neoplasia. Gynecologic involvement is extremely rare and therefore may cause relevant diagnostic confusion for both clinicians and pathologists. In this paper, we described the seventh case of ovarian malakoplakia, and we reviewed the literature to compare it with the previously reported ones. Moreover, we investigated the histologic and molecular differential diagnosis of malakoplakia, with special attention to other histiocytic disorders of gynecologic interest. Finally, we discussed the most relevant points with regard to possible pathogenesis and management. Malakoplakia often represents a forgotten entity that should be remembered preoperatively, when approaching a possible gynecologic neoplasia. Moreover, it is of remarkable importance to differentiate malakoplakia from multisystem histiocytosis involving gynecologic organs. All this would prevent misdiagnosis and overtreatment of such a rare but benign condition.

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Bilateral Ovarian Malakoplakia: Case Report and Review of the Literature With Clinical and Diagnostic Considerations

Carbone

Bonometti

Cassani

et al. 2019

International Journal of Gynecological Pathology

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Ovarian tumour-cutaneous fistula as a primary presentation of pelvic malakoplakia coexisting with a benign ovarian tumour mimicking advanced ovarian cancer

Aue-aungkul,

Muktabhant,

Kleebkaow

2024

BMJ Case Rep

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Malakoplakia is a rare granulomatous, chronic inflammatory disease generally affecting the urogenital organs, though it can arise in other organs. The clinical manifestations of malakoplakia vary depending on the affected organ. The final diagnosis is confirmed by the presence of Michaelis-Gutmann bodies on pathology. This report describes a case of pelvic malakoplakia accompanied by an ovarian tumour-cutaneous fistula, initially misdiagnosed as advanced ovarian cancer invading the anterior abdominal wall with left pleural effusion based on imaging studies and increased serum carbohydrate antigen 19-9. The patient underwent left thoracentesis and fluid collection from the fistula tract for cytology, which showed no malignancy. She underwent primary debulking surgery, including removal of the fistula tract from anterior abdominal wall. Histopathological examination revealed malakoplakia coexisting with mucinous cystadenoma of the left ovary. For postoperative management, she received prolonged oral antibiotics for 6 months. There was no evidence of disease recurrence at the 24-month follow-up.

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Angular Pregnancy, a Rare Entity of Ectopic Pregnancy

Benghanem,

Fezani,

Faïd

et al. 2024

ejmhr

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Localisation tubaire et ovarienne d’une malakoplakie: à propos d’un cas et revue de la littérature

Cited by 3 publications

References 10 publications

Bilateral Ovarian Malakoplakia: Case Report and Review of the Literature With Clinical and Diagnostic Considerations

Bilateral Ovarian Malakoplakia: Case Report and Review of the Literature With Clinical and Diagnostic Considerations

Ovarian tumour-cutaneous fistula as a primary presentation of pelvic malakoplakia coexisting with a benign ovarian tumour mimicking advanced ovarian cancer

Angular Pregnancy, a Rare Entity of Ectopic Pregnancy

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