Localisations ostéoarticulaires de la sarcoïdose

Sarcoidosis is a multisystem inflammatory disorder of unknown cause. It most commonly affects the pulmonary system but can also affect the musculoskeletal system, albeit less frequently. In patients with sarcoidosis, rheumatic involvement is polymorphic. It can be the presenting symptom of the disease or can appear during its progression. Articular involvement is dominated by nonspecific arthralgia, polyarthritis, and Löfgren's syndrome, which is defined as the presence of lung adenopathy, arthralgia (or arthritis), and erythema nodosum. Skeletal manifestations, especially dactylitis, appear mainly as complications of chronic, multiorgan sarcoidosis. Muscle involvement in sarcoidosis is rare and usually asymptomatic. The diagnosis of rheumatic sarcoidosis is based on X-ray findings and magnetic resonance imaging findings, although the definitive diagnosis is made by anatomopathological study of biopsy samples. Musculoskeletal involvement in sarcoidosis is generally relieved with nonsteroidal anti-inflammatory drugs or corticosteroids. In corticosteroid-resistant or -dependent forms of the disease, immunosuppressive therapy, such as treatment with methotrexate or anti-TNF-α, is employed. The aim of this review was to present an overview of the various types of osteoarticular and muscle involvement in sarcoidosis, focusing on their diagnosis and management.

show abstract

“…Também pode ocorrer acro-osteólise, que se apresenta como densidades nodulares nas falanges terminais. ( 17 ) …”

Section: Sarcoidose óSseaunclassified

Musculoskeletal involvement in sarcoidosis

Akasbi¹,

Zahra²,

Harzy³

2014

J. bras. pneumol.

View full text Add to dashboard Cite

show abstract

“…ci-après) dont elle partage l'évolution favorable [7,46,318,359] . ci-après) dont elle partage l'évolution favorable [7,46,318,359] .…”

Section: Arthrite Aiguëunclassified

“…Elle est rare (0,2 % des cas) et survient plus volontiers chez les patients d'origine africaine (mais les Caucasiens sont également affectés), de sexe masculin, avec d'autres manifestations viscérales anciennes de la maladie [318] . Elle évolue par poussées et rémissions .…”

Section: Arthrite Chroniqueunclassified

“…L'atteinte musculaire intéresse 50 à 80 % des patients après 2 ans mais elle est très rarement symptomatique (0,5 à 2,3 % des cas) [318] . Elle peut se traduire par des myalgies, une fatigabilité musculaire ou une tuméfaction nodulaire .…”

Section: Myopathiesunclassified

“…Elle est plus fréquente chez les femmes, notamment de moins de 40 ans [318,330] . Elle peut mimer cliniquement une polymyosite .…”

Section: Myopathie Aiguëunclassified

See 2 more Smart Citations