Localization of Radioactivity in the Lung and the Lymph Nodes

ICRP Publication 151: Occupational Intakes of Radionuclides: Part 5

“…(611) Bryant et al (1953) and Berg et al (1954) measured the uptake of 198 Aulabelled colloidal gold (3-4-nm diameter) into the hilar lymph nodes of dogs for up to $30 d after instillation into the bronchial lumen, or injection into the submucosa of a bronchus. The uptake in other organs, including the spleen and liver, was very low, indicating that little 198 Au entered the bloodstream.…”

“…Cadmium can replace zinc in several biological processes. The toxic effects of cadmium appear to result, in part, from interactions with zinc at the stage of zinc biological function (Cotzias et al., 1961; Brzoska and Moniuszko-Jakoniuk, 2001). (500) Systemic cadmium enters the urinary bladder and intestines much more slowly than zinc, and hence has a much longer residence time than zinc in the body.…”

“…Cadmium can replace zinc in several biological processes. The toxic effects of cadmium appear to result, in part, from interactions with zinc at the stage of zinc biological function (Cotzias et al., 1961; Brzoska and Moniuszko-Jakoniuk, 2001).…”