LOCALIZATION OF Tc^99m POLYPHOSPHATE IN SOFT TISSUE MALIGNANCIES

Role of technetium-99m pertechnetate scintigraphy in the management of extra-abdominal fibromatosis

“…A far greater problem than diagnosing the primary tumor is accurately judging the extent of a locally recurrent extra-abdominal fibromatosis, because a part of the recurrent tumor is often confused with operative scar tissue. Until the present study, radionuclide scans have not been routinely used in dealing with extra-abdominal fibromatosis [10,[14][15][16][17][18][19][20].…”

99Tcm-polyphosphate uptake by breast tumours

“…Large series of breast cancer scintigrams using technetium pertechnate (Richman et al, 1975b) and technetium diphosphonate (McDougall and Pistenma, 1974) have failed to confirm their value as a diagnostic screen. Although 89TcmPP frequently gives visualization of breast tumours, we do not support the contention of other workers (Weinraub et al, 1975) that it differentiates benign from malignant lesions.…”

Bone Scanning in Clinical Practice

“…Finally, Richman et al (1975) suggested that local tissue anoxia with increased lactate production and pH reduction might lead to increased tissue affinity for the 99mTc phosphate or, alternatively, an increase in release of reduced 99 m Tc from the phosphate ligand. Again, little evidence is available to support this theory.…”