Localization of the Compact‐Colony Forming Active Substance (CCFAS) of Staphylococcus aureus PS84

Isolation of a Serologically Different Compact‐Colony‐Forming Active Substance from Strains of Staphylococcus aureus

“…Compact-colony-forming active substance (CCFAS) (9) was capable of clotting various species of animal plasmas (3,5). Also, with this substance, a disseminated intravascular coagulation was experimentally demonstrated in mice (15). Recently, we successfully demonstrated serological heterogeneity among these substances.…”

“…In the past, Yoshida et al (11) postulated that compact-colony formation of Staphylococcus aureus strains in serum-soft agar (SSA) medium was the results of reaction between an alkaline-dependent polysaccharide located on the cell surface and fibrin monomer, fibrinogen degradation products, and fibronectin involved in serum (7,12,13). Compact-colony-forming active substance (CCFAS) (9) was capable of clotting various species of animal plasmas (3,5).…”