Localized argyria with pseudo‐ochronosis: A report of two cases highlighting involvement of elastic fibers

Clark, Abigale; G, Kosik; Desrosiers, Andrew S.; Tjarks, B Joel; Junkins‐Hopkins, Jacqueline M.

doi:10.1111/cup.14476

J Cutan Pathol

2023

DOI: 10.1111/cup.14476

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Localized argyria with pseudo‐ochronosis: A report of two cases highlighting involvement of elastic fibers

Abigale Clark

Kosik G

Andrew S. Desrosiers

et al.

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Localized Cutaneous Argyria at the Site of a Prior Melanoma Excision Confirmed by Scanning Electron Microscopy With Energy Dispersive X-ray Analysis

McTighe,

Taylor,

Allbritton

et al. 2023

The American Journal of Dermatopathology

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Localized cutaneous argyria is a rare condition caused by the accumulation of silver particles in the skin, leading to blue–gray discoloration. Argyria may mimic melanoma and lead to misdiagnosis. We present a patient with a history of melanoma that developed a blue–gray nodule at a prior melanoma graft. The diagnosis was confirmed using scanning electron microscopy and energy dispersive x-ray analysis. These techniques differentiate argyria from melanoma and can be performed on formalin-fixed, paraffin-embedded, tissue sections. Health care providers should be alert that argyria may mimic recurrent melanoma in patients unaware of silver exposure.

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Localized Cutaneous Argyria at the Site of a Prior Melanoma Excision Confirmed by Scanning Electron Microscopy With Energy Dispersive X-ray Analysis

McTighe,

Taylor,

Allbritton

et al. 2023

The American Journal of Dermatopathology

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show abstract

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Localized argyria with pseudo‐ochronosis: A report of two cases highlighting involvement of elastic fibers

Cited by 1 publication

References 13 publications

Localized Cutaneous Argyria at the Site of a Prior Melanoma Excision Confirmed by Scanning Electron Microscopy With Energy Dispersive X-ray Analysis

Localized Cutaneous Argyria at the Site of a Prior Melanoma Excision Confirmed by Scanning Electron Microscopy With Energy Dispersive X-ray Analysis

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