Localized Erythema Multiforme-Like Contact Dermatitis From a Knee Brace

Abstract

A 47-year-old woman developed allergic contact dermatitis (ACD) to a knee brace after anterior cruciate ligament repair, manifesting as numerous erythema multiforme-like lesions. No previous cases of ACD to this Townsend Rebel knee brace, which is commonly worn postoperatively, have been reported. The patient was treated with triamcinolone ointment, cetirizine, and diphenhydramine. On follow-up, the lesions had resolved. We share this case to increase knowledge of this reaction pattern and encourage further similar reports to clarify the nature of the reaction.

Allergic contact dermatitis to braces containing 4,4′‐diaminodiphenylmethane, a previously unreported causative agent

“…4 However, in that patient, patch testing was not performed and the exact causative agent was not identified. 6 Regarding our patient, given the absence of the original box of the orthopedic device, it was impossible to obtain precise information about the ingredients of the brace or the manufacturer's name. Therefore, to prove directly that 4,4 0 -MDA was contained within the orthopedic support and confirm the diagnosis of ACD, analysis with 1 H-NMR and HPLC-MS was carried out.…”

Localised erythema multiforme‐like reaction confined to a region of clipper burn in a dog

“…1 Localised EM in humans is uncommon and has been confined to the site of a radiation port, 5 a sequela to anthrax vaccination, 6 and contact sites with rubber gloves 7 and knee brace. 8 In dogs, skin lesions of EM typically are more generalised and bilateral, and LEM has not been reported. Possible triggers in this case include drug or infection (i.e.…”

“…Erythema multiforme in humans usually is bilateral and predominantly has an acral and facial distribution 1 . Localised EM in humans is uncommon and has been confined to the site of a radiation port, 5 a sequela to anthrax vaccination, 6 and contact sites with rubber gloves 7 and knee brace 8 . In dogs, skin lesions of EM typically are more generalised and bilateral, and LEM has not been reported.…”

“…Localised EM (LEM), a condition in which EM‐like skin lesions develop only in a confined body region, was first reported in humans in 1982 4 . Since then, there have been numerous case reports of LEM or LEM‐like dermatoses in humans 5–8 . We describe a dog with a LEM‐like clinical presentation confined to a region of clipper burn.…”

“…4 Since then, there have been numerous case reports of LEM or LEM-like dermatoses in humans. [5][6][7][8] We describe a dog with a LEM-like clinical presentation confined to a region of clipper burn.…”