Localized gastrointestinal amyloidosis presenting with protein-losing enteropathy and massive hemorrhage

Abstract

Amyloidosis of the gastrointestinal tract is usually a systemic disease. Localized gastrointestinal amyloidosis without evidence of extraintestinal involvement or an associated plasma cell dyscrasia is uncommon and does not usually cause death. We report a case of a patient with localized gastrointestinal amyloidosis who presented with protein-losing enteropathy and a fatal upper gastrointestinal bleed.

Primary localized amyloidosis of the uterine cervix during pregnancy

“…Secondary amyloidosis may occur as a result of chronic inflammation and malignant tumors . Localized amyloidosis is rare but has been reported to occur in several organs of the body, including the lung, bladder, gastrointestinal tract, breast, skin and cervix . In many cases, amyloidosis is associated with squamous cell carcinoma, but there have been three cases of localized primary amyloidosis without any gynecological malignancy .…”