Localized lichen myxoedematosus (papular mucinosis) associated with morbid obesity: report of two cases

Abstract

Cutaneous diseases are often found in obese patients but, to our knowledge, mucinous disorders have not been previously reported in association with obesity. Two cases of localized lichen myxoedematosus (papular mucinosis) in two women with morbid obesity are described. Both patients underwent a low-calorie diet for a 1-year period in one case, and for 4 months in the other one, as the only treatment. There was complete resolution of cutaneous lesions at the same time that an important weight loss was observed. Nevertheless, although spontaneous regression is not frequent, it could not be disregarded in either of these two cases.

Cutaneous mucinoses

“…122 The changes in papular mucinosis are not as characteristic. 67 94 Sclerotic features are absent.…”

“…56 A discrete papular variant also occurs. 67 Self-healing cases have been reported, 68 indicating the overlap between this entity and self-healing cutaneous mucinosis (see below). 67 Self-healing cases have been reported, 68 indicating the overlap between this entity and self-healing cutaneous mucinosis (see below).…”

"Diskret" Papüler Müsinoz: Liken Miksödematozun Nadir Bir Subtipi

“…DPM'un klinik önemi hastal›¤›n HCV veya HIV infeksiyonlar›na efllik edebilmesidir, tan›s› bu nedenle önem kazanmaktad›r 4 . Histopatolojik olarak üst ve orta dermiste diffüz veya lokal müsin birikimi, de¤iflik derecelerde fibroblast proliferasyonu vard›r, kollajen yap›m› veya skleroz yoktur 1,[14][15][16] . Ay›r›c› tan›s›nda yer alan liken planus, erüptif papüler ksantom , leiomyom ve likenoid ilaç erüpsiyonundan klinik ve histolojik olarak kolayca ayr›l›r 5 .…”

Reactive pseudotumoural papular mucinosis: a new clinicopathological presentation?

“…mucinosis is an uncommon chronic disease that is characterized by numerous small, firm, and waxy papules, which coalesce together to form plaques confined to a few areas. 2 However, nodular or pseudotumoural focal cutaneous mucinosis has also been reported as a solitary lesion. [3][4][5] Its pathogenesis is still unknown, but a stimulation of fibroblasts to induce cutaneous mucinosis has been proposed.…”

“…1 Although the lesions usually have a geographical or block-like configuration, linear configuration has also been described. 2 The lesions are most frequently localized on the upper extremities and trunk. 1,2 There have been rare case reports of Becker nevus localized on lower extremities.…”