Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living

Critcher, Shelby; Parmelee, Patricia A.; Freeborn, Todd J.

doi:10.1109/ojemb.2023.3256181

Cited by 4 publications

(2 citation statements)

References 40 publications

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“…To design such a device, bioimpedance technology is an attractive solution due to its low-cost (in comparison to other imaging modalities), safety (excitation currents are non-ionizing and below perception thresholds), and high potential for integration into wearable systems. Examples of recent reports of wearable bioimpedance systems focused on knee health (Teague et al, 2020;Critcher et al, 2023), the cardiovascular system (Wang et al, 2020;Qiu et al, 2022), and even bladder monitoring (Reichmuth et al, 2020) highlight this potential. Noyori et al reported in their review of bioimpedance for bladder monitoring that this modality has been investigated for this application as early as 1975 (Noyori et al, 2022).…”

Section: Open Access Edited Bymentioning

confidence: 99%

Impact of head-down-tilt body position on abdomen resistance for urinary bladder monitory applications

Freeborn,

Critcher,

Hooper

2024

Front.Electron.

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Tissue electrical impedance (or bioimpedance) is a quantity related to the passive, frequency-dependent electrical properties of a biological tissue and is a promising modality for continuous monitoring of relative bladder volume and bladder activity. In this study, the impact of body position [specifically 6° head-down tilt (HDT)] intended to induce fluid redistribution and, therefore, result in a change in the electrical resistance of the abdomen is evaluated. The abdomen resistance (10 kHz–100 kHz) of nine healthy young adults was measured before and after 240 min in a 6° HDT position. Over this period, the resistance increase was not statistically significant even though the average bladder volume increased by 506 mL. It was expected that the abdomen resistance would decrease with an increase in bladder volume over this period. The masking of the expected resistance decrease is attributed to the shift in the fluid from the legs/abdomen to the neck/chest caused by the HDT body position over this period. Overall, this suggests that methods to differentiate bladder volume changes from other types of fluid shifts in the body are needed for resistance-based monitoring under free-living conditions.

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Section: Open Access Edited Bymentioning

confidence: 99%

Impact of head-down-tilt body position on abdomen resistance for urinary bladder monitory applications

Freeborn,

Critcher,

Hooper

2024

Front.Electron.

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“…To this aim, other technologies may be used: infrared thermography can monitor skin temperature and indirectly assess synovial inflammation processes, which play a pivotal role in the pathophysiology of OA [10] , [11] , [12] . Interestingly, other non-invasive sensing methods, such as wearable knee bioimpedance measuring systems, have recently been used to quantify the electrical impedance of knee joint tissues, which can be correlated with knee pain during daily activities [13] . Additionally, while some efforts are still needed to mature portable imaging acquisition system technologies for common practice use, tele-ultrasonography may offer a remote, repeatable, cost-effective, and rapid assessment of knee joint internal structures in the future [14] .…”

Section: Introductionmentioning

confidence: 99%

Usability Assessment of Technologies for Remote Monitoring of Knee Osteoarthritis

Cafarelli,

Sorriento,

Marola

et al. 2024

IEEE Open J. Eng. Med. Biol.

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Goal : To evaluate the usability of different technologies designed for a remote assessment of knee osteoarthritis. Methods: We recruited eleven patients affected by mild or moderate knee osteoarthritis, eleven caregivers, and eleven clinicians to assess the following technologies: a wristband for monitoring physical activity, an examination chair for measuring leg extension, a thermal camera for acquiring skin thermographic data, a force balance for measuring center of pressure, an ultrasound imaging system for remote echographic acquisition, a mobile app, and a clinical portal software. Specific questionnaires scoring usability were filled out by patients, caregivers and clinicians. Results: The questionnaires highlighted a good level of usability and user-friendliness for all the technologies, obtaining an average score of 8.7 provided by the patients, 8.8 by the caregivers, and 8.5 by the clinicians, on a scale ranging from 0 to 10. Such average scores were calculated by putting together the scores obtained for the single technologies under evaluation and averaging them. Conclusions: This study demonstrates a high level of acceptability for the tested portable technologies designed for a potentially remote and frequent assessment of knee osteoarthritis.

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Digitally Controllable Multifrequency Impedance Emulator for Bioimpedance Hardware Validation

Semenov,

Freeborn

2024

Circuit Theory & Apps

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The accurate emulation of the electrical impedance of biological tissues is crucial for the development and validation of bioimpedance measurement devices and algorithms. This paper describes a digitally controllable impedance emulator capable of reproducing values representative of tissue bioimpedance in user‐specified resistance, reactance, and frequency ranges up to 1 MHz. The presented solution uses a 2R‐1C impedance model to emulate the impedance characteristics of a biological tissue. Specific selection of each element value in this model is achieved using analog multiplexers with low resistance. A MATLAB algorithm was developed for value estimation using target impedance requirements. An example design to emulate impedance from 1 kHz to 1 MHz with 10 to 400 resistance and maximum reactance is provided. The nonideal behavior of this design was evaluated and compared against experimentally collected impedance measurements. Deviations of <1% were observed between experimental and theoretical resistances for values up to 100 kHz (with approximately 5% deviations up to 1 MHz) and reactance deviations were also <1% up to 10 kHz. High frequency deviations are attributed to the parasitic capacitance in the realization of the design. The experimental results validate the design approach and realization for low frequencies. Overall, the innovation of the proposed approach is the control of both resistance and reactance for emulating electrical impedance representative of biological tissues.

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Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living

Cited by 4 publications

References 40 publications

Impact of head-down-tilt body position on abdomen resistance for urinary bladder monitory applications

Impact of head-down-tilt body position on abdomen resistance for urinary bladder monitory applications

Usability Assessment of Technologies for Remote Monitoring of Knee Osteoarthritis

Digitally Controllable Multifrequency Impedance Emulator for Bioimpedance Hardware Validation

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