“…As the disease progresses, some atypical symptoms may appear, such as chest pain, cough, sputum production, weakness and weight loss. Early pleural SFT is also asymptomatic [8,9], but disease development may result in some typical manifestations. Hypertrophic osteoarthropathy is observed in about 20% of cases, which may result from production of hyaluronic acid or hepatocyte growth factor by the tumor [10-12].…”