General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.-Users may download and print one copy of any publication from the public portal for the purpose of private study or research. -You may not further distribute the material or use it for any profit-making activity or commercial gain -You may freely distribute the URL identifying the publication in the public portal -vi Acknowledgement Principally, I would like to express my immeasurable gratitude and appreciation to my supervisor Professor John Dalsgaard Sørensen and my co-supervisor Professor Michael Havbro Faber, who initiated this PhD research project at Aalborg University in collaboration with Danish Hydrocarbon Research and Technology Centre (DHRTC). I am deeply thankful to them for their expert guidance, untiring and invaluable support, encouragements, useful suggestions, and constructive criticism throughout the course of this research work at Aalborg University, despite their busy schedules. In addition, I would like to specially thank my assistant cosupervisor Dr. Jianjun Quin, for his constructive criticism, impactful suggestion and advice, and comments, and for sharing from his expert experience on various technical subjects matters relating to the scopes of this PhD study.My appreciation also goes to Danish Hydrocarbon Research and Technology Centre (DHRTC) for sponsoring this research work and providing practical information/data. My special thanks go to our contacts at DHRTC, most especially Kitt Anita Ravnkilde and Christian Husum Frederiksen for their unwavering supports, expert opinions, and for sharing their valuable technical-know-how, which are useful in elucidating the operations/interventions and operational challenges of sub-surface well, and for sharing the numerous representative production and operating data used in this PhD study. I am very grateful to my colleagues at Aalborg University especially Kashif Ali, Yue Guan and Juan Gonzalo Sepúlveda Astudillo for their collaborations, supports, friendship and technical opinions on several subject matters. They made the work environment feels good, which further provided the motivation that sustained me throughout the duration of this PhD study, and they made my stay in Aalborg feels like a home away from home, and I will remain thankful that our paths crossed. Special thanks go to my mother-in law Alhaja Funke Okumodi for her unparalleled encouragement through her prayers and unrelenting push, I am indeed appreciating the efforts you displayed in several other ways to support my family and for your unfailing confidence in me. Not to say the list I strongly recognize the efforts and prayers of my siblings and in-laws, most especially Mrs. Oluwafunke Adejuwon Akinsanya, who when I think of during the PhD study, boost my motivation to work harder and smarter....