LoCKAmp: lab-on-PCB technology for <3 minute virus genetic detection
Sotirios Papamatthaiou,
James Boxall-Clasby,
Edward J. A. Douglas
et al.
Abstract:The recent COVID-19 outbreak highlighted the need for Lab-on-Chip diagnostic technology fit for real-life deployment in the field. Existing bottlenecks in multistep analytical microsystem integration and upscalable, standardized fabrication techniques...
“…36–41 Some other systems utilize external pumps to control the fluid in the microchips. 42–47 These devices are able to perform the extraction, purification and amplification of nucleic acids, while they still need external setups, which certainly adds inconvenience for on-site testing. Wu et al developed a droplet magnetic-controlled microfluidic chip in which different reagents were sealed in isolated droplets respectively and the operators can transfer nucleic acids via moving the magnetic beads using a permanent magnet.…”
Genetically modified (GM) food is still highly controversial nowadays. Due to the disparate policies and attitudes worldwide, demands for a rapid, cost-effective and user-friendly GM crops identification method are increasingly...
“…36–41 Some other systems utilize external pumps to control the fluid in the microchips. 42–47 These devices are able to perform the extraction, purification and amplification of nucleic acids, while they still need external setups, which certainly adds inconvenience for on-site testing. Wu et al developed a droplet magnetic-controlled microfluidic chip in which different reagents were sealed in isolated droplets respectively and the operators can transfer nucleic acids via moving the magnetic beads using a permanent magnet.…”
Genetically modified (GM) food is still highly controversial nowadays. Due to the disparate policies and attitudes worldwide, demands for a rapid, cost-effective and user-friendly GM crops identification method are increasingly...
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