Locomotion-dependent auditory gating to the parietal cortex mediates flexible multisensory decisions
Ilsong Choi,
Seung-Hee Lee
Abstract:Decision-making in mammals is fundamentally based on the integration of several senses. When different sensory inputs guide conflicting outcomes, animals make decisions following the prepotent sensory modality. However, the neural basis of state-dependent flexibility in sensory dominance and multisensory decisions remains obscure. Here, we found that locomotion switched auditory-dominant decisions to visual-dominant ones in mice with audiovisual conflicts. When mice made auditory-dominant decisions, the visual… Show more
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