Locomotive syndrome: clinical perspectives

Ikemoto, Tatsunori; Arai, Young‐Chang P.

doi:10.2147/cia.s148683

Cited by 44 publications

(52 citation statements)

References 70 publications

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“…Although the original concept of LS included musculoskeletal disorders such as osteoarthritis, spondylosis and osteoporosis, recent studies have indicated that LS involves psychological disorders as well (Ikemoto et al, 2016;Nakamura et al, 2017a). Previous studies also indicated that LS, frailty and sarcopenia may contribute similarly in terms of the physical aspect of functional decline among older individuals (Ikemoto & Arai, 2018;Yoshimura et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Assessment of locomotive syndrome among older individuals: a confirmatory factor analysis of the 25-question Geriatric Locomotive Function Scale

Wang

Ikemoto

Hirasawa

et al. 2020

PeerJ

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Background The 25-question Geriatric Locomotive Function Scale (GLFS-25) is widely used in daily clinical practice in evaluating locomotive syndrome (LS). The questionnaire contains 25 questions aiming to describe 6 aspects, including body pain, movement-related difficulty, usual care, social activities, cognitive status, and daily activities. However, its potential underlying latent factor structure of the questionnaire has not been fully examined so far. Methods Five hundred participants who were 60 years or older and were able to walk independently with or without a cane but had complaints of musculoskeletal disorders were recruited face to face at the out-patient ward of Aichi Medical University Hospital between April 2018 and June 2019. All participants completed the GLFS-25. Confirmatory factor analysis (CFA) models (single-factor model, 6-factor model as designed by the developers of the GLFS-25) were fitted and compared using Mplus 8.3 with a maximum likelihood minimization function. Modification indices, standardized expected parameter change were used, a standard strategy for scale development was followed in the search for an alternative and simpler model that could well fit the collected data. Cronbach’s α and its 95% confidence interval (CI) were also calculated. Results Mean (standard deviation) participants age was 72.6 (7.4) years old; 63.6% of them were women. Under the current criteria, 132 (26.4%) and 262 (52.4%) of the study subjects would be classified as LS stage 1 and stage 2, respectively. Overall, the Cronbach’s α (95% CI) for GLFS-25 evaluated using these data was 0.959 (0.953, 0.964). The single- and 6-factor models were rejected due to poor fit. The alternative models with either full 25 questions or a shortened GLFS-16 were found to fit the data better. These alternative models included three latent factors (body pain, movement-related difficulty, and psycho-social complication) and allowed for cross-loading and residual correlations. Discussion The findings of the CFA models provided evidence that the factor structure of the GLFS-25 might be simpler than the 6-factor model as suggested by the designers. The complex relationships between the latent factors and the observed items may also indicate that individual sub-scale use or simply combining the raw scores for evaluation is likely to be inadequate or unsatisfactory. Thus, future revisions of the scoring algorithm or questions of the GLFS-25 may be required.

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Section: Introductionmentioning

confidence: 99%

Assessment of locomotive syndrome among older individuals: a confirmatory factor analysis of the 25-question Geriatric Locomotive Function Scale

Wang

Ikemoto

Hirasawa

et al. 2020

PeerJ

Self Cite

View full text Add to dashboard Cite

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“…LS is proposed as a disorder that predominantly affects people who are at a high risk of developing a musculoskeletal ambulation disability attributed to locomotor organ diseases [28]. In LS, the locomotive system consists of three main components: (1) bones, (2) joints and intervertebral discs, and (3) muscles and nerves [29]. LS refers to the conditions under which the elderly have been receiving care services, or high-risk conditions under which they may soon require care services linked to problems in their locomotive organs [30].…”

Section: Discussionmentioning

confidence: 99%

Locomotive Syndrome is a Risk Factor for the Dropout of Continuous Positive Airway Pressure Treatment in Patients with Obstructive Sleep Apnea Syndrome

et al. 2020

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Objective: The purpose of this study was to investigate the risk factors linked to patient dropout from continuous positive airway pressure (CPAP) therapy for the treatment of obstructive sleep apnea syndrome (OSAS). Methods: This study included 1191 patients with OSAS at baseline assessment, who were followed for 3 years. We evaluated clinical parameters, indicators related to OSAS treatment, exercise habits and the presence of locomotive syndrome (LS). LS was evaluated by a ‘loco-check’, as established by the Japanese Orthopedic Association. The OSAS patients were categorized at baseline as belonging to an ‘LS group’ or a ‘non-LS group’, and clinical parameters were compared. Results: Eighty-six patients (7.2%) dropped out of CPAP therapy during the 3 year follow-up period. The dropout rate of the LS group was significantly higher than that of the non-LS group. Using a Cox-proportional hazard model, the LS, old age and poor compliance were determined to be significant risk factors for dropping out of CPAP therapy. The hazard ratios (95% CI) of LS, elderly people and poor CPAP compliance were 2.11 (1.31–3.48), 1.80 (1.11–2.94) and 1.61 (1.04–2.47), respectively. Conclusion: LS may be the critical risk factor for dropping out of CPAP therapy among patients with OSAS.

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“…The con-current criterion validity was conducted between GLFS25 and EQ-5D (European Quality of Life-5 dimensions) and its Pearson correlation coefficient was found as 0.86. The cut-off score for diagnosis of LS was set at 16 (sensitiv-ity=0.88, specificity=0.84) in Iranian elders [14]. The obtained data were presented with descriptive statistics.…”

Section: Methodsmentioning

confidence: 99%