Locus of Control Orientation in Panic Disorder and the Differential Effects of Treatment

Bakker, A.; Spinhoven, Philip; Does, Willem Van der; Balkom, A.J.L.M. van; Dyck, Richard van

doi:10.1159/000049350

Cited by 23 publications

(20 citation statements)

References 14 publications

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“…We were especially interested in the possible influence of locus of control orientation (a multidimensional concept indicating a patient's beliefs about the controllability of the panic disorder) on differential effectiveness of the two treatment groups. As Bakker, Spinhoven, van der Does, van Balkom, and van Dyck (2002) concluded, "another interesting question that needs further research is the possibility that locus of control orientation constitutes a prescriptive indicator, that is, a variable predicting differential response to one versus another treatment" (p. 61).…”

Section: Real Data Example: the Treatment Of Panic Disorder Studymentioning

confidence: 99%

“…All locus of control scales were measured by the Multidimensional Anxiety Locus of Control scale (MALC; Bakker et al, 2002). We recoded the four locus of control scales described by Bakker et al (2002) in such a way that a higher score on a scale indicated a higher specific locus of control. In addition, De-test Anxiety was used as a covariate, and Post-test Anxiety was the outcome variable (y; both variables were measured by the HAMA).…”

Section: Real Data Example: the Treatment Of Panic Disorder Studymentioning

confidence: 99%

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The regression trunk approach to discover treatment covariate interaction

Dusseldorp

Meulman

2004

Psychometrika

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The regression trunk approach (RTA) is an integration of regression trees and multiple linear regression analysis. In this paper RTA is used to discover treatment covariate interactions, in the regression of one continuous variable on a treatment variable with multiple covariates. The performance of RTA is compared to the classical method of forward stepwise regression. The results of two simulation studies, in which the true interactions axe modeled as threshold interactions, show that RTA detects the interactions in a higher number of cases (82.3% in the first simulation study, and 52.3% in the second) than stepwise regression (56.5% and 20.5%). In a real data example the final RTA model has a higher cross-validated variance-accounted-for (29.8%) than the stepwise regression model (12.5%). All of these results indicate that RTA is a promising alternative method for demonstrating differential effectiveness of treatments.

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Section: Real Data Example: the Treatment Of Panic Disorder Studymentioning

confidence: 99%

Section: Real Data Example: the Treatment Of Panic Disorder Studymentioning

confidence: 99%

The regression trunk approach to discover treatment covariate interaction

Dusseldorp

Meulman

2004

Psychometrika

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“…In addition, it has been emphasized that enhancing mastery and confidence in self-control are important ingredients in anxiety management treatments [11]. LOC evolved from a general concept indicating a person’s expectation about how reinforcement is controlled [12] to more specific concepts, for example, a patient’s beliefs about the controllability of an anxiety disorder (the Multidimensional Anxiety Locus of Control scale [13]). Liberman [14] investigated the influence of LOC in a small sample of psychiatric outpatients who were referred for psychotherapy.…”

Section: Introductionmentioning

confidence: 99%

“…This method finds one or more optimal thresholds on a predictor variable. Internal LOC and medication LOC are two of the four subscales measured by the Multidimensional Anxiety Locus of Control Scale [13]. We were also interested in the possible influence of the other two subscales (therapist LOC and chance LOC).…”

Section: Introductionmentioning

confidence: 99%

Which Panic Disorder Patients Benefit from Which Treatment: Cognitive Therapy or Antidepressants?

Dusseldorp

Spinhoven

Bakker

et al. 2007

Psychother Psychosom

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Background: Beliefs about the controllability of a disorder may be relevant in the causation, maintenance and treatment of disorders. We investigated whether congruence between patients’ beliefs about controllability of a panic disorder and the type of treatment provided predicted outcome. Methods: The differential effectiveness of cognitive therapy and antidepressant treatment (paroxetine or clomipramine) was investigated in a sample of 129 panic disorder patients in a 12-week, pretest posttest placebo-controlled study. Panic frequency, agoraphobic avoidance, anxiety, depression, and disability were measured with various validated interviewer and self-report measures. Beliefs about controllability were measured with the Multidimensional Anxiety Locus of Control Scale measuring an internal, chance, therapist and medication locus of control. In order to analyze aptitude-treatment interactions a new strategy called the Regression Trunk Approach was used in addition to classical hierarchical multiple regression analysis. Results: Using the Regression Trunk Approach we found that locus of control orientation (LOC) predicted the differential effectiveness of cognitive therapy. Those patients with a medium internal LOC who received cognitive therapy performed significantly better than all patients who received a placebo pill on 8 of the 10 outcome variables. We did not find a differential LOC effect for antidepressant treatment. No evidence for aptitude-treatment interactions using hierarchical multiple regression analysis was found. Conclusions: Moderately strong beliefs about self-control of panic disorder congruent with the cognitive intervention provided seem to moderate treatment effectiveness. Future studies must be more attentive to the nonlinear effects of patient characteristics on the outcome of different types of treatments.

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“…23,24 Finally, cognitive behavioral therapy and other psychotherapeutic interventions have proven efficacy with both PD and MDD. [25][26] Aims of the study: 1-To estimate the frequency of agoraphobia in PD and the related sex difference. 2-To estimate the comorbidity rate of MDD in PD and the related sex difference.…”

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confidence: 99%

The frequency of agoraphobia and the comorbidity of major depressive disorder in panic disorder

Tahir

2012

ZJMS

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Background and objectives: Panic disorder (PD) is a common disabling psychiatric condition that has a considerable impact on the quality of life. This study was done to estimate the frequency of agoraphobia and the comorbidity of major depressive disorder (MDD) in PD, with related sex difference. Methods: A cross sectional descriptive study, was done on patients who consulted a private psychiatric clinic for features of PD, in Erbil city from August 2009 to August 2010. A convenient sample of 118 patients, 73 females and 45 males, having PD with or without agoraphobia were taken after giving their informed verbal consent. All patients were checked for the presence of MDD. The diagnoses were done clinically, and then checked according to the diagnostic and statistical manual of mental disorders, 4th edition, text revision (DSM-IV-TR). Results: Mean age of PD with or without agoraphobia was 31.1 years. Female to male ratio was 1.6/1. Mean age at onset was 26.3 years. Mean duration of illness was 4.4 years. Patients having PD without Agoraphobia were 81.4%, while having PD with agoraphobia were 18.6% in which the males (20%) affected more than females (17.8%). The comorbidity rate of MDD (mild to severe degree) in PD was 61% with higher males (68.9%) than females (57.5%). Conclusion:The majority of patients with PD in our sample had a comorbid MDD. Early detection and management of PD is necessary to reduce complications and improve their quality of life.

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Locus of Control Orientation in Panic Disorder and the Differential Effects of Treatment

Cited by 23 publications

References 14 publications

The regression trunk approach to discover treatment covariate interaction

The regression trunk approach to discover treatment covariate interaction

Which Panic Disorder Patients Benefit from Which Treatment: Cognitive Therapy or Antidepressants?

The frequency of agoraphobia and the comorbidity of major depressive disorder in panic disorder

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