“…It stands for a new approach to the problem of Thrombophilia Risk, which is centred on a formal framework based on LP for Knowledge Representation and Reasoning, is subject to formal proof, being complemented with an ANN approach to computing that caters for the handling of incomplete, unknown, or even self-contradictory information. The extensions of the predicates that make the universe of discourse are given in terms of QoIs and DoCs that stand, respectively, for the arguments Quality-of-Information and one's Degree-of-Confidence that the predicates argument values fit into a given interval considering their respective domains, being the data/information/knowledge under analyse either unknown, incomplete, or even self-contradictory (Neves et al, 2015;Neves, Silva, Neves, & Vicente, 2016). The presented approach presents a worthy performance in the diagnosis of thrombophilia, due to the sensitivity and specificity which exhibited values near 96%.…”