Logistic Regression Model to Distinguish Between the Benign and Malignant Adnexal Mass Before Surgery: A Multicenter Study by the International Ovarian Tumor Analysis Group

Timmerman, Dirk; Testa, Antonia Carla; Bourne, Tom; Ferrazzi, E.; Ameye, Lieveke; Konstantinovic, Maya L; Calster, Ben Van; Collins, William P.; Vergote, Ignace; Huffel, Sabine Van; Valentin, Lil

doi:10.1200/jco.2005.01.7632

Cited by 430 publications

(458 citation statements)

References 28 publications

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“…Transvaginal sonography has dramatically improved the ability to diagnose ovarian lesions, providing reliable criteria and indications for surgery [11,12]. The bizarre echogenicity of some endometriomas can erroneously suggest malignancy and vice versa.…”

Section: Endometrioma Diagnostic Imaging and Implications For Treatmentmentioning

confidence: 99%

Imaging for the evaluation of endometriosis and adenomyosis

Exacoustòs

Manganaro

Zupi

2014

Best Practice & Research Clinical Obstetrics & Gynaecol

211

143

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Endometriosis affects between 5 and 45% of women in reproductive age, is associated with significant morbidity, and constitutes a major public health concern. The correct diagnosis is fundamental in defining the best treatment strategy for endometriosis. Therefore, non-invasive methods are required to obtain accurate diagnoses of the location and extent of endometriotic lesions. Transvaginal sonography and magnetic resonance imaging are used most frequently to identify and characterise lesions in endometriosis. Subjective impression by an experienced sonologist for identifying endometriomas by ultrasound showed a high accuracy. Adhesions can be evaluated by real-time dynamic transvaginal sonography, using the sliding sign technique, to determine whether the uterus and ovaries glide freely over the posterior and anterior organs and tissues. Diagnosis is difficult when ovarian endometriomas are absent and endometriosis causes adhesions and deep infiltrating nodules in the pelvic organs. Magnetic resonance imaging seems to be useful in diagnosing all locations of endometriosis, and its diagnostic accuracy is similar to those obtained using ultrasound. Transvaginal ultrasound has been proposed as first line-line imaging technique because it is well accepted and widely available. The main limitation of ultrasound concerns lesions located above the rectosigmoid junction owing to the limited field-of-view of the transvaginal approach and low accuracy in detecting upper bowel lesions by transabdominal ultrasound. A detailed non-invasive diagnosis of the extension in the pelvis of endometriosis can facilitate the choice of a safe and adequate surgical or medical treatment

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Section: Endometrioma Diagnostic Imaging and Implications For Treatmentmentioning

confidence: 99%

Imaging for the evaluation of endometriosis and adenomyosis

Exacoustòs

Manganaro

Zupi

2014

Best Practice & Research Clinical Obstetrics & Gynaecol

211

143

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“…In 1999, International Ovarian Tumor Analysis Group performed a study which included multiple centers from five European countries. They collected relevant demographic and radiographic data of more than 1,000 patients presenting with persistent adnexal masses prospectively and developed a mathematic model so that the risk of risk of malignancy in an adnexal mass can be calculated, with an area under the receiver operating curve (ROC) of 0.96 (Timmerman et al, 2005).…”

Section: Role Of Ultrasound In Characterization Of Ovarian Massesmentioning

confidence: 99%

Role of Ultrasound in Characterization of Ovarian Masses

Hafeez¹,

Sufian²,

Beg³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…In studies where pattern recognition was compared to other ultrasound methods (Lerner score [111], risk of malignancy index [112], the Tailor risk calculation model [113], the Timmerman risk calculation model [114] and the mathematical risk calculation models designed in the International Ovarian Tumor Analysis (IOTA) study [115]), pattern recognition was superior to the other methods for distinguishing benign from malignant adnexal masses (Table 7) [115][116][117].…”

Section: Palpable Pelvic Massmentioning

confidence: 99%

Imaging in gynecology

Valentin

2006

Best Practice & Research Clinical Obstetrics & Gynaecol

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This chapter summarizes the diagnostic performance (sensitivity, specificity, positive and negative likelihood ratios) of ultrasound, computer tomography, and magnetic resonance imaging in the diagnosis of various gynecological diseases and tumors. Positron emission tomography is not discussed. Imaging in infertility, in the diagnosis of Mullerian duct anomalies and in gynecological oncology (staging of gynecological cancers, diagnosis of recurrence of gynecological cancer, diagnosis of trophoblastic tumors) is not dealt with.Ultrasound is the first line imaging method for discrimination between viable intrauterine pregnancy, miscarriage and tubal pregnancy in women with bleeding and/or pain in early pregnancy, for discrimination between benign and malignant adnexal masses and for making a specific diagnosis in adnexal tumors (e.g., dermoid cyst, endometrioma, hemaorrhagic corpus luteum, ectetera), for diagnosing intracavitary uterine pathology in women with bleeding problems, and for confirming or refuting pelvic pathology in women with pelvic pain. Magnetic resonance imaging may have a role as a secondary test in the diagnosis of adenomyosis, 'deep endometriosis' (e.g., endometriosis in the rectovaginal septum or in the utero-sacral ligaments), and in the diagnosis of extremely rare types of ectopic pregnancy (e.g., in the spleen, liver or retroperitoneum).

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Logistic Regression Model to Distinguish Between the Benign and Malignant Adnexal Mass Before Surgery: A Multicenter Study by the International Ovarian Tumor Analysis Group

Abstract: Because the model was constructed from multicenter data, it is more likely to be generally applicable. The effectiveness of the model will be tested prospectively at different centers.

Cited by 430 publications

References 28 publications

Imaging for the evaluation of endometriosis and adenomyosis

Imaging for the evaluation of endometriosis and adenomyosis

Role of Ultrasound in Characterization of Ovarian Masses

Imaging in gynecology

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