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Abstract

(Rev Med Chile 2013; 141: 870-878).

Prevalence of Cardioprotective Medication Use in Coronary Heart Disease Patients in South America: Systematic review and Meta-Analysis

“…Most studies were conducted in Brazil [ 3 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 ]. Six studies were conducted in Argentina [ 59 60 61 62 63 64 ], four in Chile [ 65 66 67 68 ], four in Colombia [ 69 70 71 72 ], three in Uruguay [ 73 74 75 ] and two were multi-country studies conducted in Argentina, Brazil, Chile and Colombia [ 12 ] and Brazil and Suriname [ 76 ]. The most common language of the articles was English (58 articles), followed by Spanish (11 articles) and Portuguese (4 articles).…”

“…Articles considering the prescription rates adequate still noted that medication use decreased with time after diagnosis [ 59 75 ], indicating that there is room to improve medication adherence and secondary prevention of CHD [ 59 ]. It is noteworthy that some publications report that achievement of cardiovascular risk factor targets was inadequate despite high levels of medication use [ 59 66 67 75 80 ], which may be attributed to the use of suboptimal doses [ 59 ].…”

“…Half of them reported that medication use was low [59,62,[76][77][78] or insufficient compared to guideline recommendations [2,12,48,61,79]. Other articles reported that cardioprotective medication use was adequate or high [32,60,66,67,73,75], or in line with guideline recommendations [38,65,80].…”