Long-acting injectable buprenorphine for opioid use disorder: A systematic review of impact of use on social determinants of health

Martin, Emily T.; Maher, Hayley; McKeon, Gemma; Patterson, Sue; Blake, Julie A.; Chen, Kai Yang

doi:10.1016/j.jsat.2022.108776

Cited by 9 publications

(3 citation statements)

References 53 publications

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“…The introduction of long‐acting injectable buprenorphine (LAIB) preparations has changed the treatment landscape for opioid use disorder, allowing consumers to undergo opioid substitution therapy that is tailored to their individual circumstances and having a positive impact on individual social determinants of health (Martin et al, 2022). As a treatment for opioid use disorder, LAIB is typically used as a monthly injection administered by a qualified clinician, and several studies have shown improved treatment retention and access through using this preparation to treat opioid use disorder (Andrada et al, 2022; Lofwall & Fanucchi, 2021).…”

Section: Introductionmentioning

confidence: 99%

Exploring the effectiveness of a regional nurse practitioner led, long‐acting injectable buprenorphine‐based model of care for opioid use disorder

Strike¹,

D'Angelo-Kemp²,

Searby

2023

Int J Mental Health Nurs

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The introduction of long‐acting injectable buprenorphine preparations for opioid use disorder has been widely heralded as a breakthrough treatment, with several studies indicating positive results when using these medications. In many locations, nurse practitioners prescribe, administer, and monitor long‐acting injectable preparations. The objective of this paper is to explore whether a reduction in dispensed needles and syringes is attributable to increased nurse practitioner prescribing of LAIB. We used a retrospective audit of needles dispensed through the health service needle and syringe program vending machine, and individuals treated with long‐acting injectable buprenorphine by the nurse practitioner led model. In addition, we examined potential factors that may influence changes in the number of needles dispensed. Linear regression found that each individual with opioid dependence treated with long‐acting injectable buprenorphine was associated with 90 fewer needles dispensed each month (p < 0.001). The nurse practitioner led model of care for individuals with opioid dependence appears to have influenced the number of needles dispensed at the needle and syringe program. Although all confounding factors could not be discounted entirely, such as substance availability, affordability, and individuals obtaining injecting equipment elsewhere, our research indicates that a nurse practitioner led model of treating individuals with opioid use disorder influenced needle and syringe dispensing in the study setting.

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Section: Introductionmentioning

confidence: 99%

Exploring the effectiveness of a regional nurse practitioner led, long‐acting injectable buprenorphine‐based model of care for opioid use disorder

Strike¹,

D'Angelo-Kemp²,

Searby

2023

Int J Mental Health Nurs

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“…LAIBs have been shown overall to positively impact on the social determinants of health. 9 This case series explores direct induction onto high-dose Buvidal Weekly 24 mg or 32 mg or Buvidal Monthly 128 mg without prior stabilisation on either sublingual buprenorphine or lower-strength Buvidal Weekly preparations.…”

mentioning

confidence: 99%

Direct induction onto high-dose long-acting injectable buprenorphine: A case series

Naren,

Cook,

MacCartney

2024

Australas Psychiatry

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Introduction This case series reports on five patients with opioid use disorder (OUD) who were commenced directly onto high-dose long-acting injectable buprenorphine (LAIB). Method A retrospective audit and manual review of the electronic medical record at cohealth Innerspace was conducted for patients who had been directly inducted onto high-dose LAIB. Results Five cases were identified on retrospective manual file review. All patients identified were males aged between 33 and 60 years old and were treated with either high-dose Buvidal Weekly and Monthly preparations. No immediate significant adverse effects were noticed and 4 out of 5 remain engaged with treatment. Conclusion This case series shows it is possible to directly induct patients with OUD onto high-dose LAIB preparations without significant side effects or harm to the patient and could be considered a viable option in the treatment of patients with OUD.

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“…OST prescribing is typically the remit of general practitioners (GPs), however research has identified an ageing cohort of prescribers and several barriers to new GPs taking on this work (Longman et al, 2011(Longman et al, , 2012. Further, the introduction of the long-acting injectable buprenorphine preparation has become a mainstay of treatment for opioid dependence (Barnett et al, 2021;Martin et al, 2022), and specialist AOD treatment roles have moved into areas beyond what would be considered 'traditional' treatment settings, such as emergency departments and community health services; many health services have moved to this model of care to implement wider screening and brief intervention, particularly for alcohol use (Nordeck et al, 2018;Reeve et al, 2016).…”

mentioning

confidence: 99%

Barriers and facilitators to becoming an alcohol and other drug nurse practitioner in Australia: A mixed methods study

Searby

Burr

Blums³

et al. 2023

Int J Mental Health Nurs

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Alcohol and other drug (AOD) nurse practitioners have an advanced scope of practice that allows them to diagnose, prescribe pharmacological treatments for alcohol and other substance use disorders, and monitor physical and mental health. The Behaviour Change Wheel (BCW) is used to understand barriers and facilitators to implementation by applying three conditions of behaviour change (capability, opportunity, and motivation—the COM‐B framework). The aim of this paper is to describe the current AOD nurse practitioner workforce, and to explore barriers and facilitators to AOD nurse practitioner uptake in Australia. A mixed method approach was used in this study: a survey to determine the current state of the AOD nurse practitioner workforce (n = 41) and qualitative interviews with 14 participants to determine barriers to endorsement and ongoing work as a nurse practitioner. Interview transcripts were analysed using thematic analysis and mapped to the COM‐B framework. The AOD nurse practitioner is a highly specialized provider of holistic care to people who use alcohol and other drugs, with AOD nurse practitioners performing advanced roles such as prescribing and medication management. However, there are several barriers to the further uptake of AOD nurse practitioners in Australia, including varied organizational support, a lack of support for the higher study required to become a nurse practitioner and a lack of available positions. Arguably, nurse practitioners are key to addressing prescriber shortages inherent in AOD treatment settings. In addition, they are equipped to provide true holistic care. We recommend that barriers are addressed to expand the AOD nurse practitioner workforce in Australia.

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Long-acting injectable buprenorphine for opioid use disorder: A systematic review of impact of use on social determinants of health

Cited by 9 publications

References 53 publications

Exploring the effectiveness of a regional nurse practitioner led, long‐acting injectable buprenorphine‐based model of care for opioid use disorder

Exploring the effectiveness of a regional nurse practitioner led, long‐acting injectable buprenorphine‐based model of care for opioid use disorder

Direct induction onto high-dose long-acting injectable buprenorphine: A case series

Barriers and facilitators to becoming an alcohol and other drug nurse practitioner in Australia: A mixed methods study

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