Long-lived coherences for line-narrowing in high-field NMR

Sarkar, Riddhiman; Ahuja, Puneet; Vasos, Paul R.; Bornet, Aurélien; Wagnières, Olivier; Bodenhausen, Geoffrey

doi:10.1016/j.pnmrs.2010.10.002

Cited by 40 publications

(53 citation statements)

References 23 publications

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“…First, the study of polarization transfer and assignments of LACs gives additional spectroscopic information, since the transfer frequencies and LAC positions are uniquely related to the NMR parameters of a spin system. Second, ZQCs can be long-lived, [47][48][49][50] allowing determination of very small J-couplings.…”

Section: Discussionmentioning

confidence: 99%

Exploiting level anti-crossings for efficient and selective transfer of hyperpolarization in coupled nuclear spin systems

Pravdivtsev

Yurkovskaya

Kaptein

et al. 2013

Phys. Chem. Chem. Phys.

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Spin hyperpolarization can be coherently transferred to other nuclei in field-cycling NMR experiments.At low magnetic fields spin polarization is redistributed in a strongly coupled network of spins.Polarization transfer is most efficient at fields where level anti-crossings (LACs) occur for the nuclear spin-states. A further condition is that field switching to the LAC positions is non-adiabatic in order to convert the starting population differences into spin coherences that cause time-dependent mixing of states. The power of this method has been demonstrated by studying transfer of photo-Chemically Induced Dynamic Nuclear Polarization (photo-CIDNP) in N-acetyl-tryptophan. We have investigated the magnetic field dependence and time dependence of coherent CIDNP transfer and directly assessed nuclear spin LACs by studying polarization transfer at specific field positions. The proposed approach based on LACs is not limited to CIDNP but is advantageous for enhancing NMR signals by spin order transfer from any type of hyper-polarized nuclei.

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Section: Discussionmentioning

confidence: 99%

Exploiting level anti-crossings for efficient and selective transfer of hyperpolarization in coupled nuclear spin systems

Pravdivtsev

Yurkovskaya

Kaptein

et al. 2013

Phys. Chem. Chem. Phys.

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“…8 Current applications of pure singlet states are mainly optimization of generation of hyperpolarization in PHIP related experiments, [13][14][15] and storage of hyperpolarization in long-lived spin states (LLS) 16,17 and in long-lived coherences (LLC). 18 In this contribution we are (1) giving an amendment to the interpretation of photo-PHIP experiments as it was given in the original paper, 8 as well as (2) a generalization of the theoretical description of spin evolution of photo-PHIP in weakly coupled multi-spin systems 19 that is confirmed by experimental observation.…”

Section: Introductionmentioning

confidence: 99%

Coherent evolution of singlet spin states in PHOTO-PHIP and M2S experiments

Pravdivtsev

Yurkovskaya

Петров

et al. 2017

Phys. Chem. Chem. Phys.

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A consistent theoretical description of the spin dynamics underlying photo-PHIP (para-hydrogen induced polarization) experiments is given and validated experimentally: spectra from zero-quantum coherence (ZQC) ''in-phase'' and ''out-of-phase'' were obtained and evolution of ZQCs and the proposed and the fundamental principles of ZQ spectroscopy are formulated. This investigation opens a new way to obtain information on the sign of J-couplings using ZQ spectroscopy. The proposed method is also useful to track the redistribution of the singlet spin population in various PHIP related experiments, which is essential for efficient polarization transfer to target nuclei.

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“…In weakly oriented phases, one can measure residual dipolar couplings (RDCs). [23] These splittings contain information about distances and order parameters and are widely used in the determination of three-dimensional structures and dynamics of biomolecules.…”

Section: Long-lived States (Lls)mentioning

confidence: 99%

Extending Timescales and Narrowing Linewidths in NMR

Segawa

Bornet

Salvi

et al. 2011

Chimia

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Among the different fields of research in nuclear magnetic resonance (NMR) which are currently investigated in the Laboratory of Biomolecular Magnetic Resonance (LRMB), two subjects that are closely related to each other are presented in this article. On the one hand, we show how to populate long-lived states (LLS) that have long lifetimes T LLS which allow one to go beyond the usual limits imposed by the longitudinal relaxation time T 1 . This makes it possible to extend NMR experiments to longer time-scales. As an application, we demonstrate the extension of the timescale of diffusion measurements by NMR spectroscopy. On the other hand, we review our work on long-lived coherences (LLC), a particular type of coherence between two spin states that oscillates with the frequency of the scalar coupling constant J IS and decays with a time constant T LLC . Again, this time constant T LLC can be much longer than the transverse relaxation time T 2 . By extending the coherence lifetimes, we can narrow the linewidths to an unprecedented extent. J-couplings and residual dipolar couplings (RDCs) in weakly-oriented phases can be measured with the highest precision.

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Long-lived coherences for line-narrowing in high-field NMR

Cited by 40 publications

References 23 publications

Exploiting level anti-crossings for efficient and selective transfer of hyperpolarization in coupled nuclear spin systems

Exploiting level anti-crossings for efficient and selective transfer of hyperpolarization in coupled nuclear spin systems

Coherent evolution of singlet spin states in PHOTO-PHIP and M2S experiments

Extending Timescales and Narrowing Linewidths in NMR

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