Long Survival Following Bacterial Meningitis-Associated Brain Destruction

Repertinger, Susan; Fitzgibbons, William P.; Omojola, Mathew F.; Brumback, Roger A.

doi:10.1177/08830738060210070401

Cited by 67 publications

(41 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…15,16 There were a total of 1012 reported sequelae, of which a majority were behavioral and/or intellectual deficits (n ϭ 792, 78.3%). Specific diagnoses and conditions include low intelligence quotient (IQ)/ cognitive impairment (n ϭ 455, 45.0%), attention deficit hyperactivity disorder (n ϭ 24, 2.4%), and behavioral deficits (n ϭ 77, 7.6%).…”

Section: Resultsmentioning

confidence: 99%

Long-term Sequelae of Childhood Bacterial Meningitis

Chandran¹,

Herbert²,

Misurski³

et al. 2011

Pediatric Infectious Disease Journal

144

View full text Add to dashboard Cite

A majority of childhood bacterial meningitis survivors with long-term sequelae that are documented in the literature have academic and behavioral limitations. While neurologic deficits may resolve over time, subtle behavioral deficits may not be appreciated initially and may continue to affect survivors for many years. Further studies are needed to quantify the true societal and economic burden of long-term sequelae as well as fully understand the breadth of types of sequelae that survivors experience.

show abstract

Section: Resultsmentioning

confidence: 99%

Long-term Sequelae of Childhood Bacterial Meningitis

Chandran¹,

Herbert²,

Misurski³

et al. 2011

Pediatric Infectious Disease Journal

144

View full text Add to dashboard Cite

show abstract

“…Given the cited cases-the oldest patient (T.K.) being twenty-four years old and pre-pubescent when he suffered whole-brain death (Repertinger et al 2006)-it appears that the organic systems of young children, possibly up to some point around the onset of puberty, are more "plastic" than those of more mature human beings. 25 Perhaps the integrative functions normally carried out by the brainstem in mature human beings can be taken on by other, normally less critical, neural structures in young children or even adolescents.…”

Section: Resultsmentioning

confidence: 99%

A Thomistic Defense of Whole-Brain Death

Eberl

2015

Linacre Q

View full text Add to dashboard Cite

Michel Accad critiques the currently accepted whole-brain criterion for determining the death of a human being from a Thomistic metaphysical perspective and, in so doing, raises objections to a particular argument defending the whole-brain criterion by Patrick Lee and Germain Grisez. In this paper, I will respond to Accad's critique of the whole-brain criterion and defend its continued validity as a criterion for determining when a human being's death has occurred in accord with Thomistic metaphysical principles. I will, however, join Accad in criticizing Lee and Grisez's proposed defense of the whole-brain criterion as potentially leading to erroneous conclusions regarding the determination of human death. Lay summary Catholic physicians and bioethicists currently debate the legally accepted clinical standard for determining when a human being has died—known as the “wholebrain criterion”—which has also been morally affirmed by the Magisterium. This paper responds to physician Michel Accad's critique of the whole-brain criterion based upon St. Thomas Aquinas's metaphysical account of human nature as a union of a rational soul and a material body. I defend the whole-brain criterion from the same Thomistic philosophical perspective, while agreeing with Accad's objection to an alternative Thomistic defense of whole-brain death by philosophers Patrick Lee and Germain Grisez.

show abstract

“…11 The bodies of such patients manifest many holistic properties, such as homeostasis, proportional growth, and overcoming intercurrent illnesses. These factors include direct damage to vital organs by the initial etiology, secondary damage to those organs from sympathetic storm during brain herniation, a widespread inflammatory reaction to tissue damage, and autonomic dysfunction from spinal shock.…”

Section: Incoherence Between Concept and Criterionmentioning

confidence: 99%

Brain Death: A Conclusion in Search of a Justification

Shewmon¹

2018

Hastings Center Report

View full text Add to dashboard Cite

At its inception, “brain death” was proposed not as a coherent concept but as a useful one. The 1968 Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death gave no reason that “irreversible coma” should be death itself, but simply asserted that the time had come for it to be declared so. Subsequent writings by chairman Henry Beecher made clear that, to him at least, death was essentially a social construct, and society could define it however it pleased. The first widely endorsed attempt at a philosophical justification appeared thirteen years later, with a report from the President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research and a seminal paper by James Bernat, Charles Culver, and Bernard Gert, which introduced the insightful tripartite scheme of concept, criterion, and tests for death. Their paper proposed that the correct concept of death is the “permanent cessation of functioning of the organism as a whole,” which tenuously remains the mainstream concept to this day. In this essay, I focus on this mainstream concept, arguing that equating brain death with death involves several levels of incoherence: between concept and criterion, between criterion and tests, between tests and concept, and between all of these and actual brain death praxis.

show abstract

Long Survival Following Bacterial Meningitis-Associated Brain Destruction

Cited by 67 publications

References 15 publications

Long-term Sequelae of Childhood Bacterial Meningitis

Long-term Sequelae of Childhood Bacterial Meningitis

A Thomistic Defense of Whole-Brain Death

Brain Death: A Conclusion in Search of a Justification

Contact Info

Product

Resources

About