Long-term Appearance of Lacerations Repaired Using a Tissue Adhesive

Simon, Harold K.; McLario, David J.; Bruns, Thomas; Zempsky, William T.; Rj, Wood; Sullivan, Kevin M.

doi:10.1542/peds.99.2.193

Cited by 69 publications

(35 citation statements)

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“…Nineteen articles were selected as potentially relevant. [11][12][13][14][15][16][17][18][19][20][21][22][23][32][33][34][35][36][37] One additional article, 38 identified through the Cochrane Wounds Group Specialized Trials Register, was considered potentially relevant based on the title. The reviewers identified two additional abstracts 24,39 during regular review of a current emergency medicine journal, which had yet to be indexed in Medline.…”

Section: Resultsmentioning

confidence: 99%

“…[11][12][13][14][15][16][17][18][20][21][22][23][24] Three of the unique studies were represented by more than one publication, due to either separate reporting of early and late cosmetic outcomes 12,16,17,21 or analysis of the results subgrouped by other variables. 14,[21][22][23] Two articles await further assessment. 38,39 The remaining seven excluded articles were comprised of three review articles, 34,35,37 two studies dealing with operative incisions or other wounds, 32,36 one study dealing with high-tension lacerations across joints, 19 and one study that did not include TAs.…”

Section: Resultsmentioning

confidence: 99%

“…38,39 The remaining seven excluded articles were comprised of three review articles, 34,35,37 two studies dealing with operative incisions or other wounds, 32,36 one study dealing with high-tension lacerations across joints, 19 and one study that did not include TAs. 33 Eight studies compared a TA versus SWC, four with butylcyanoacrylate 11,12,18,[20][21][22] and four with octylcyanoacrylate. 13,14,16,17,23,24 The SWC method was sutures in five studies, 11,12,[16][17][18][20][21][22] adhesive strips in one study, 24 and a mixture of closure methods in the remaining two studies, 13,14,23 though the majority of patients received sutures.…”

Section: Resultsmentioning

confidence: 99%

“…4 There is an increasing amount of literature supporting the use of TAs for various minor lacerations, [5][6][7][8][9][10] including a number of randomized controlled trials (RCTs) that support TAs in their respective study populations. [11][12][13][14][15][16][17][18][19][20][21][22][23][24] However, due to the wide variation in study parameters, there are no generalizable, definitive answers about the effectiveness of TAs.…”

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confidence: 99%

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Tissue Adhesives for Traumatic Lacerations: A Systematic Review of Randomized Controlled Trials*

Farion

2003

Academic Emergency Medicine

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Objective: To summarize the best available evidence for the effect of tissue adhesives (TAs) in managing traumatic lacerations in children and adults. Methods: A search was conducted using the Cochrane Controlled Trials Register, Medline, and EMBase for relevant studies. The authors also searched the citations of selected studies and contacted relevant authors and manufacturers. The search included randomized controlled trials (RCTs) comparing a TA versus standard wound closure (sutures, staples, adhesive strips) (SWC) or two TAs for acute, linear, low-tension, traumatic lacerations in an emergency or primary care setting. Data were extracted by one reviewer and checked for accuracy by a second reviewer. Two reviewers independently assessed masked copies for quality. Outcomes of cosmesis (subgroups of age, wound location, and need for deep sutures), pain, procedure time, ease of use, and complications were analyzed separately for two comparisons: 1) TA versus SWC; and 2) TA versus TA. Results: Eight studies compared a TA with SWC. No significant difference was found for cosmesis at any time point examined. Subgroup analysis was possible only for age; no significant difference was found. Pain scores [Parent Visual Analogue Scale weighted mean difference (VAS WMD) ¼ ÿ15.7 mm; 95% CI ¼ ÿ21.9 to ÿ9.5] and procedure time (WMD ¼ ÿ5.7 minutes; 95% CI ¼ ÿ8.2 to ÿ3.1) significantly favored TAs. Small, statistically significant risk differences were found for dehiscence [favoring SWC; number needed to harm (NNH) ¼ 25; 95% CI ¼ 14 to 100] and erythema (favoring TAs; NNH ¼ 8; 95% CI ¼ 4 to 100). Only one study compared two TAs (butylcyanoacrylate versus octylcyanoacrylate) for pediatric facial lacerations. No significant difference was found for cosmesis, pain, procedure time, or complications. Conclusions: TAs are an acceptable alternative to SWC for simple traumatic lacerations. No difference in cosmesis was found between TAs and SWC, or between different TAs. Tissue adhesives offer the benefits of decreased procedure time and less pain, compared with SWC. A small increased rate of dehiscence with TAs must be considered when choosing the closure method (NNH ¼ 25).

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

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Tissue Adhesives for Traumatic Lacerations: A Systematic Review of Randomized Controlled Trials*

Farion

2003

Academic Emergency Medicine

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“…128,129 Tissue adhesives, such as octyl cyanoacrylate, provide essentially painless closure for low-tension wounds. 130,131 Steri-Strips (3M, St Paul, MN) provide similar painless closure and are less expensive than currently available tissue adhesives. 132 Absorbable sutures should be considered for facial wounds that must be sutured to avoid the pain and anxiety produced by suture removal.…”

Section: Controlling Pain Related To Needle Sticks and Other Minor Prmentioning

confidence: 99%

Relief of Pain and Anxiety in Pediatric Patients in Emergency Medical Systems

Zempsky¹,

Cravero²,

Shaw³

et al. 2012

Pediatrics

Self Cite

291

179

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Control of pain and stress for children is a vital component of emergency medical care. Timely administration of analgesia affects the entire emergency medical experience and can have a lasting effect on a child' s and family' s reaction to current and future medical care. A systematic approach to pain management and anxiolysis, including staff education and protocol development, can provide comfort to children in the emergency setting and improve staff and family satisfaction. Pediatrics 2012;130:e1391-e1405 BACKGROUND A systematic approach to pain management is required to ensure relief of pain and anxiety for children who enter into the emergency medical system, which includes all emergency medical services (EMS) agencies, interfacility critical care transport teams, and the emergency department (ED). 1 The administration of appropriate analgesia in children varies by age as well as by training of the ED team (which includes physicians, nurses, physician assistants, and nurse practitioners), however, and still lags behind analgesia provided for adults in similar situations. 2 Furthermore, neonates are at highest risk of receiving inadequate analgesia. 3,4 Encouragingly, improvements in the recognition and treatment of pain in children have led to changes in the approach to pain management for acutely ill and injured pediatric patients. 5 Studies have shown an increase in opiate use in children with fractures. [6][7][8] Recent advances in the approach and support for pediatric analgesia and sedation, as well as new products and devices, have improved the overall climate of the ED for patients and families in search of the "ouchless" ED. 5,9 Increased parental education regarding pain and sedation, physician comfort and desire to enhance patient satisfaction, and a quest to satisfy accreditation regulations have appropriately driven this effort. System-wide approaches for pain management awareness and strategies work best if they are woven into the fabric of the emergency medical system through education and protocol development. The purpose of this report was to provide information to optimize the comfort and minimize the distress of children and families as they are cared for in the emergency setting.

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A Prospective Comparison of Octyl Cyanoacrylate Tissue Adhesive (Dermabond) and Suture for the Closure of Excisional Wounds in Children and Adolescents

Bernard

Doyle²,

Friedlander³

et al. 2001

Arch Dermatol

103

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Long-term Appearance of Lacerations Repaired Using a Tissue Adhesive

Abstract: The use of HAB is an ideal alternative to conventional suturing for the cutaneous closure of low tension lacerations in children with a long-term cosmetic outcome comparable to conventional suturing.

Cited by 69 publications

References 1 publication

Tissue Adhesives for Traumatic Lacerations: A Systematic Review of Randomized Controlled Trials*

Tissue Adhesives for Traumatic Lacerations: A Systematic Review of Randomized Controlled Trials*

Relief of Pain and Anxiety in Pediatric Patients in Emergency Medical Systems

A Prospective Comparison of Octyl Cyanoacrylate Tissue Adhesive (Dermabond) and Suture for the Closure of Excisional Wounds in Children and Adolescents

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