Long-term assessment of functional capacity, muscle function, lung function, and quality of life in survivors of ventilator-associated pneumonia

Dias, Larissa Mello; da Cruz, Jenipher Angel; Lopes, Agnaldo José

doi:10.1016/j.heliyon.2023.e23431

Cited by 1 publication

(1 citation statement)

References 33 publications

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“…Previous studies showed that the pulmonary function of patients is compromised [18,28,29] and is marked by reduced lung capacity and volume and respiratory muscle weakness [18,30]; however, there are gradual improvements in FEV1 and FVC [18,[31][32][33], especially following interventions [34]. Hence, the lung functions of surviving patients with acute lung infections are expected to improve and may be normal in the majority of patients [35]. In our study, we have not found significant changes in lung functions in non-COVID-19 patients, and this might reflect that the majority of non-COVID-19 patients had no severe acute lung problems, which could acutely compromise their lung functions.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life, Family Support, Spirometry, and 6-Minute Walking Distance Differences between COVID-19 and Non-COVID-19 Intensive Care Unit Patients in One Year Following Hospital Discharge

Avgeri,

Mantzarlis,

Gerovasileiou

et al. 2024

Healthcare

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Background: Critically ill patients after Intensive Care Unit (ICU) discharge may present disability in their cognitive and physical functions. Objectives: To investigate the quality of life (QoL) of both COVID-19 and non-COVID-19 patients following ICU discharge, lung function, and physical performance of participants. Methods: This study was prospective and conducted between 2020 and 2021 in the “X” hospital. If patients were Mechanically-Ventilated (MV) > 48 h, they were included. Results: Fifty COVID-19 and seventy-two non-COVID-19 participants were included in this study. The mean (SD) of the total SF-36 scores at COVID-19 patients at hospital discharge and 3 and 12 months were 46.5 (14.5), 68.6 (17.8), and 82.3 (8.9) (p < 0.05), while non-COVID-19 participants were 48.5 (12.1), 72.2 (9.9), and 82.7 (5.4) (p < 0.05). The forced expiratory volume in one second (FEV1) and 6-minute walking distance (6MWD) were assessed at 3 and 12 months and significantly improved over 12 months. Conclusion: The QoL of COVID-19 patients improved significantly over time as FEV1 and 6MWD.

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